AASPE is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
Jean-Paul CONCORDET
Jean-Paul CONCORDET
Chargé de recherche
Affiliated entity
Équipe GE2R
Contact
Phone
01 40 79 37 09
Responsibilities in the research group
Directeur adjoint
Publications
2022
- , December 2022 — Base-editing-mediated dissection of a \gamma-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression. Nature Communications. Vol. 13, n° 1, dir. Nature Publishing Group, p. 6618.
- , July 2022 — Disease modeling by efficient genome editing using a near PAM-less base editor in vivo. Nature Communications. Vol. 13, n° 1, dir. Nature Publishing Group, p. 3435.
- , 2022 — CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis. Human Molecular Genetics. Vol. 31, n° 1, dir. Oxford University Press (OUP), p. 41-56.
2021
- , December 2021 — « Tagging Proteins with Fluorescent Reporters Using the CRISPR/Cas9 System and Double-Stranded DNA Donors » in Multiprotein Complexes. P. 39-57.
- , October 2021 — Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Human Gene Therapy. Vol. 32, 19-20, dir. Mary Ann Liebert, p. 1059-1075.
- , March 2021 — Correction of \beta-thalassemia by CRISPR/Cas9 editing of the \alpha-globin locus in human hematopoietic stem cells. Blood Advances. Vol. 5, n° 5, dir. The American Society of Hematology, p. 1137-1153.
- , March 2021 — Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish. eLife. Vol. 10, dir. eLife Sciences Publication.
- , 2021 — Gene Tagging with the CRISPR-Cas9 System to Facilitate Macromolecular Complex Purification. Methods in molecular biology (Clifton, N.J.). Vol. 2305, p. 153-174.
2020
- , July 2020 — Characterization of post-edited cells modified in the TFAM gene by CRISPR/Cas9 technology in the bovine model. PLoS ONE. Vol. 15, n° 7, dir. Public Library of Science, e0235856.
- , July 2020 — Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins. Nature Communications. Vol. 11, n° 1, dir. Nature Publishing Group, p. 3778.