Affiliation entity
Équipe SANTÉ


patrizia.alberti [at]
01 40 79 37 27

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France


Responsibilities inside unit

Directrice Adjointe

Responsable du Pôle Biophysique




  • Chatain Jean, Hatem Georges, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, September 2021Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
  • Chatain Jean, Blond Alain, Phan Anh Tuân, Saintomé Carole & Alberti Patrizia, July 2021GGGCTA repeats can fold into hairpins poorly unfolded by replication protein A: a possible origin of the length-dependent instability of GGGCTA variant repeats in human telomeres. Nucleic Acids Research , , dir. {Oxford University Press}
  • Gurung Pratima, Gomes Ana Rita, Martins Rafael, Juranek Stefan, Alberti Patrizia, Mbang-Benet Diane-Ethna, Urbach S, Gazanion Elodie, Guitard Vincent, Paeschke Katrin & Lopez-Rubio José Juan, April 2021PfGBP2 is a novel G-quadruplex binding protein in Plasmodium falciparum. Cellular Microbiology vol. 23, n° 4, dir. {Wiley} e13303
  • Tran Phong Lan Thao, Rieu Martin, Hodeib Samar, Joubert Alexandra, Ouellet Jimmy, Alberti Patrizia, Bugaut Anthony, Allemand Jean-François, Boulé Jean-Baptiste & Croquette Vincent, 2021Folding and persistence times of intramolecular G-quadruplexes transiently embedded in a DNA duplex. Nucleic Acids Research , , dir. {Oxford University Press}
  • Gazanion Elodie, Lacroix Laurent, Alberti Patrizia, Gurung Pratima, Wein Sharon, Cheng Mingpan, Mergny Jean-louis, Gomes Ana Rita & Lopez‑rubio José‑juan, July 2020Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites. PLoS Genetics vol. 16, n° 7, dir. {Public Library of Science} e1008917
  • Lancrey Astrid, Safa Layal, Chatain Jean, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, March 2018The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units. Biochimie vol. 146, , dir. {Elsevier} p. 68-72
  • Saintomé C., Alberti Patrizia, Guinot N., Lejault P., Chatain J., Mailliet P., Riou Jean-Francois & Bugaut A., 2018Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures. Chemical Communications vol. 54, n° 15, dir. {Royal Society of Chemistry} p. 1897-1900
  • Solé Anna, Delagoutte Emmanuelle, Ciudad Carlos, Noé Véronique & Alberti Patrizia, February 2017Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group}
  • Safa Layal, Gueddouda Nassima Meriem, Thiébaut Frédéric, Delagoutte Emmanuelle, Petruseva Irina, Lavrik Olga, Mendoza Oscar, Bourdoncle Anne, Alberti Patrizia, Riou Jean-François & Saintomé Carole, 20165’ to 3’ Unfolding Directionality of DNA Secondary Structures by Replication Protein A. Journal of Biological Chemistry vol. 291, n° 40, dir. {American Society for Biochemistry and Molecular Biology} p. 21246-21256
  • Saintomé Carole, Amrane Samir, Mergny Jean-louis & Alberti Patrizia, January 2016The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium. Nucleic Acids Research vol. 44, n° 6, dir. {Oxford University Press} p. 2926-2935