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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Pipier A., Devaux A., Lavergne T., Adrait A., Couté Y., Britton S., Calsou P., Riou J., Defrancq E. & Gomez D., December 2021 — Constrained G4 structures unveil topology specificity of known and new G4 binding proteins. Scientific Reports vol. 11, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/s41598-021-92806-8
Chatain Jean, Hatem Georges, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
https://dx.doi.org/10.1093/nar/gkab768
Bossaert Madeleine, Pipier Angélique, Riou Jean-Francois, Noirot Céline, Nguyễn Linh-Trang, Serre Remy-Felix, Bouchez Olivier, Defrancq Eric, Calsou Patrick, Britton Sébastien & Gomez Dennis, June 2021 — Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands. G-quadruplexes (G4) are non-canonical DNA structures found in the genome of most species including human. Small molecules… eLife vol. 10, , dir. eLife Sciences Publications, Ltd e65184
ISSN
2050-084X
https://dx.doi.org/10.7554/eLife.65184
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  • Patrizia ALBERTI
  • Emmanuelle DELAGOUTTE
  • Carole SAINTOMÉ

Year

  • (-) 2021

Affiliation entity

  • Équipe GPA
  • Équipe SANTÉ

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  • CNRS
  • MNHN
  • Sorbonne Université

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A research group
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