AASPE is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
Jean-François RIOU,
List of publications
, June 2021 — Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands. G-quadruplexes (G4) are non-canonical DNA structures found in the genome
of most species including human. Small molecules... eLife. Vol. 10, dir. eLife Sciences Publications, Ltd, e65184.
ISSN:
2050-084X
, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research. Vol. 49, dir. Oxford University Press, p. 10735-10746.
, December 2021 — Constrained G4 structures unveil topology specificity of known and new G4 binding proteins. Scientific Reports. Vol. 11, n° 1, dir. Nature Publishing Group.