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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • GE2R _ Genome Editing, DNA double-strand break Repair and cellular Responses
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Marlin Fanny, Simon Philippe, Bonneau Stéphanie, Alberti Patrizia, Cordier Céline, Boix Charlotte, Perrouault Loïc, Fossey Aurélie, Saison-Behmoaras Tula, Fontecave Marc & Giovannangeli Carine, November 2012 — Flavin Conjugates for Delivery of Peptide Nucleic Acids. ChemBioChem vol. 13, n° 17, dir. {Wiley-VCH Verlag}
https://dx.doi.org/10.1002/cbic.201200505
Ménoret Séverine, de Cian Anne, Tesson Laurent, Remy Séverine, Usal Claire, Boulé Jean-Baptiste, Boix Charlotte, Fontanière Sandra, Crénéguy Alison, Nguyen Tuan H., Brusselle Lucas, Thinard Reynald, Gauguier Dominique, Concordet Jean-Paul, Cherifi Yacine et al., October 2015 — Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins. Scientific Reports vol. 5, , dir. {Nature Publishing Group} p. 14410
https://dx.doi.org/10.1038/srep14410
de Cian Anne, Grellier Philippe, Mouray Elisabeth, Depoix Delphine, Bertrand Hélène, Monchaud David, Teulade-Fichou Marie-Paule, Mergny Jean-Louis & Alberti Patrizia, November 2008 — Plasmodium Telomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds. ChemBioChem vol. 9, n° 16, dir. {Wiley-VCH Verlag} p. 2730-2739
https://dx.doi.org/10.1002/cbic.200800330
Bertrand Hélène, Monchaud David, de Cian Anne, Guillot Régis, Mergny Jean-Louis & Teulade-Fichou Marie-Paule, 2007 — The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes. Organic & Biomolecular Chemistry vol. 5, n° 16, dir. {Royal Society of Chemistry} p. 2555
https://dx.doi.org/10.1039/B708635K
de Cian Anne, Delemos Elsa, Mergny Jean-Louis, Teulade-Fichou Marie-Paule & Monchaud David, February 2007 — Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds. Journal of the American Chemical Society vol. 129, n° 7, dir. {American Chemical Society} p. 1856-1857
https://dx.doi.org/10.1021/ja067352b
Menoret Séverine, Ouisse Laure-Hélène, Tesson Laurent, Delbos Frédéric, Garnier Delphine, Remy Severine, Usal Claire, Concordet Jean-Paul, Giovannangeli Carine, Chenouard Vanessa, Brusselle Lucas, Mérieau Emmanuel, Nerrière-Daguin Véronique, Duteille Franck, Bellier-Waast Frédérique et al., 2018 — Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models. Transplantation vol. 102, n° 8, dir. {Lippincott, Williams \& Wilkins} p. 1271-1278
https://dx.doi.org/10.1097/TP.0000000000002251
Remy Séverine, Chenouard Vanessa, Tesson Laurent, Usal Claire, Ménoret Séverine, Brusselle Lucas, Heslan Jean-Marie, Nguyen Tuan Huan, Bellien Jeremy, Merot Jean, De Cian Anne, Giovannangeli Carine, Concordet Jean-Paul & Anegon Ignacio, November 2017 — Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group} p. 16554
https://dx.doi.org/10.1038/s41598-017-16328-y
Tesson Laurent, Remy Severine, Ménoret Séverine, Usal Claire, Thinard Reynald, Savignard Chloé, de Cian Anne, Giovannangeli Carine, Concordet Jean-Paul & Anegon Ignacio, 2016 — « Genome Editing in Rats Using TALE Nucleases » in TALENs. Methods in Molecular Biology.. , , p. 245-259
https://dx.doi.org/10.1007/978-1-4939-2932-0_18
Eckenfelder Agathe, Ségéral Emmanuel, Pinzón Natalia, Ulveling Damien, Amadori Céline, Charpentier Marine, Nidelet Sabine, Concordet Jean-Paul, Zagury Jean-François, Paillart Jc, Berlioz-Torrent Clarisse, Seitz Hervé, Emiliani Stéphane & Gallois-Montbrun Sarah, April 2017 — Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent manner. Nucleic Acids Research vol. 45, n° 7, dir. {Oxford University Press} p. 4158-4173
https://dx.doi.org/10.1093/nar/gkw1289
Auer Thomas O., Xiao Tong, Bercier Valerie, Gebhardt Christoph, Duroure Karine, Concordet Jean-Paul, Wyart Claire, Suster Maximiliano, Kawakami Koichi, Wittbrodt Joachim, Baier Herwig & Bene Filippo Del, June 2015 — Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3. eLife vol. 4, , dir. {eLife Sciences Publication} e05061
https://dx.doi.org/10.7554/eLife.05061.030
Renaud Jean-Baptiste, Boix Charlotte, Charpentier Marine, deCian Anne, Cochennec Julien, Duvernois-Berthet Evelyne, Perrouault Loïc, Tesson Laurent, Edouard Joanne, Thinard Reynald, Cherifi Yacine, Menoret Séverine, Fontanière Sandra, de Crozé Noémie, Fraichard Alexandre et al., March 2016 — Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases.. Cell Reports vol. 14, n° 9, dir. {Elsevier Inc} p. 2263-72
https://dx.doi.org/10.1016/j.celrep.2016.02.018
Larcher Thibaut, Lafoux Aude, Tesson Laurent, Remy Severine, Thepenier Virginie, François Virginie, Le Guiner Caroline, Goubin Hélicia, Dutilleul Maeva, Guigand Lydie, Toumaniantz Gilles, de Cian Anne, Boix Charlotte, Renaud Jean-Baptiste, Cherel Yan et al., 2014 — Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy. PLoS ONE vol. 9, n° 10, dir. {Public Library of Science} 13 p.
https://dx.doi.org/10.1371/journal.pone.0110371
Geny Sylvain, Pichard Simon, Brion Alice, Renaud Jean-Baptiste, Jacquemin Sophie, Concordet Jean-Paul & Poterszman A., December 2021 — « Tagging Proteins with Fluorescent Reporters Using the CRISPR/Cas9 System and Double-Stranded DNA Donors » in Multiprotein Complexes.. , , p. 39-57
https://dx.doi.org/10.1007/978-1-0716-1126-5_3
Rosello Marion, Vougny Juliette, Czarny François, Mione Marina, Concordet Jean-Paul, Albadri Shahad & del Bene Filippo, February 2021 — Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish. eLife vol. 10, , dir. {eLife Sciences Publication}
https://dx.doi.org/10.7554/elife.65552
Khosravi Mohammad Ali, Abbasalipour Maryam, Concordet Jean-Paul, Berg Johannes Vom, Zeinali Sirous, Arashkia Arash, Azadmanesh Kayhan, Buch Thorsten & Karimipoor Morteza, July 2019 — Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease. European Journal of Pharmacology vol. 854, , dir. {Elsevier} p. 398-405
https://dx.doi.org/10.1016/j.ejphar.2019.04.042
Khosravi Mohammad Ali, Abbasalipour Maryam, Concordet Jean-Paul, Berg Johannes Vom, Zeinali Sirous, Arashkia Arash, Buch Thorsten & Karimipoor Morteza, February 2020 — Expression analysis data of BCL11A and \gamma-globin genes in KU812 and KG-1 cell lines after CRISPR/Cas9-mediated BCL11A enhancer deletion. Data in Brief vol. 28, , dir. {Elsevier} p. 104974
https://dx.doi.org/10.1016/j.dib.2019.104974
De Cian Anne, Cristofari G., Reichenbach P., De Lemos E., Monchaud David, Teulade-Fichou Marie-Paule, Shin-Ya K., Lacroix L., Lingner J. & Mergny Jean-Louis, October 2007 — Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action.. Proceedings of the National Academy of Sciences of the United States of America vol. 104, n° 44, dir. {National Academy of Sciences} p. 17347-52
https://dx.doi.org/10.1073/pnas.0707365104
Lema Ingrid J., Amazit Larbi, Lamribet Khadija, Fagart Jérome, Blanchard Anne, Lombès Marc, Cherradi Nadia & Viengchareun Say, December 2017 — HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group} p. 4835
https://dx.doi.org/10.1038/s41598-017-04838-8
Lema Ingrid J., Amazit Larbi, Lamribet Khadija, Fagart Jérome, Blanchard Anne, Lombès Marc, Cherradi Nadia & Viengchareun Say, December 2017 — RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity. Cellular and Molecular Life Sciences vol. 74, n° 24, dir. {Springer Verlag} p. 4587-4597
https://dx.doi.org/10.1007/s00018-017-2594-x
Viengchareun Say, Lema Ingrid J., Lamribet Khadija, Keo Vixra, Blanchard Anne, Cherradi Nadia & Lombès Marc, September 2014 — Hypertonicity Compromises Renal Mineralocorticoid Receptor Signaling through Tis11b-Mediated Post-Transcriptional Control. Journal of the American Society of Nephrology vol. 25, n° 10, dir. {American Society of Nephrology} p. 2213-2221
https://dx.doi.org/10.1681/ASN.2013091023
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  • Patrizia ALBERTI
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