AASPE is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
List of publications
, June 2021 — Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands. G-quadruplexes (G4) are non-canonical DNA structures found in the genome
of most species including human. Small molecules... eLife. Vol. 10, dir. eLife Sciences Publications, Ltd, e65184.
ISSN:
2050-084X
, July 2021 — GGGCTA repeats can fold into hairpins poorly unfolded by replication protein A: a possible origin of the length-dependent instability of GGGCTA variant repeats in human telomeres. Nucleic Acids Research. Dir. Oxford University Press.
, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research. Vol. 49, dir. Oxford University Press, p. 10735-10746.
, November 2021 — Gain-of-Function Mutations in RPA1 Cause a Syndrome with Short Telomeres and Somatic Genetic Rescue. Blood. Dir. American Society of Hematology.
, January 2021 — Effect of DNA repair inhibitor AsiDNA on the incidence of telomere fusion in crisis. Human Molecular Genetics. Dir. Oxford University Press (OUP).
, 2021 — Folding and persistence times of intramolecular G-quadruplexes transiently embedded in a DNA duplex. Nucleic Acids Research. Dir. Oxford University Press.
, July 2020 — Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites. PLoS Genetics. Vol. 16, n° 7, dir. Public Library of Science, e1008917.
, December 2020 — PfGBP2 is a novel G-quadruplex binding protein in Plasmodium falciparum. Cellular Microbiology. Dir. Wiley.
, 2020 — AP-TSS: A New Method for the Analysis of RNA Expression from Particular and Challenging Transcription Start Sites. Biomolecules. Vol. 10, n° 6, dir. MDPI, p. 827.
, June 2020 — Sex-Specific Response to Caloric Restriction After Reproductive Investment in Microcebus murinus: An Integrative Approach. Frontiers in Physiology. Vol. 11, dir. Frontiers.
, February 2019 — Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA). Molecules. Vol. 24, n° 3, dir. MDPI, p. 577.
, June 2019 — Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. International Journal of Molecular Sciences. Vol. 20, n° 11, dir. MDPI, p. 2791.
, 2018 — Photoactivatable oligonucleotide probes to trap single-stranded DNA binding proteins: Updating the potential of 4-thiothymidine from a comparative study. Biochimie. Vol. 154, dir. Elsevier, p. 164-175.
, March 2018 — The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units. Biochimie. Vol. 146, dir. Elsevier, p. 68-72.
, 2018 — Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures. Chemical Communications. Vol. 54, n° 15, dir. Royal Society of Chemistry, p. 1897-1900.
, August 2018 — Probing hyper-negatively supercoiled mini-circles with nucleases and DNA binding proteins. PLoS ONE. Vol. 13, n° 8, dir. Public Library of Science, e0202138.
, February 2018 — Metabolic and genomic adaptations to winter fattening in a primate species, the grey mouse lemur (Microcebus murinus). International Journal of Obesity. Vol. 42, n° 2, dir. Nature Publishing Group, p. 221-230.
, February 2017 — Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes. Scientific Reports. Vol. 7, n° 1, dir. Nature Publishing Group.
, 2016 — 5’ to 3’ Unfolding Directionality of DNA Secondary Structures by Replication Protein A. Journal of Biological Chemistry. Vol. 291, n° 40, dir. American Society for Biochemistry and Molecular Biology, p. 21246-21256.
, January 2016 — The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium. Nucleic Acids Research. Vol. 44, n° 6, dir. Oxford University Press, p. 2926-2935.