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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • GE2R _ Genome Editing, DNA double-strand break Repair and cellular Responses
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Ramaen Odile, Joubert Alexandra, Simister Philip, Belgareh-Touzé Naïma, Olivares-Sanchez Maria Conception, Zeeh Jean-Christophe, Chantalat Sophie, Golinelli-Cohen Marie-Pierre, Jackson Catherine L, Biou Valérie & Cherfils Jacqueline, September 2007 — Interactions between conserved domains within homodimers in the BIG1, BIG2, and GBF1 Arf guanine nucleotide exchange factors.. Journal of Biological Chemistry vol. 282, n° 39, dir. {American Society for Biochemistry and Molecular Biology} p. 28834-42
https://dx.doi.org/10.1074/jbc.M705525200
Tran Phong Lan Thao, Rieu Martin, Hodeib Samar, Joubert Alexandra, Ouellet Jimmy, Alberti Patrizia, Bugaut Anthony, Allemand Jean-François, Boulé Jean-Baptiste & Croquette Vincent, 2021 — Folding and persistence times of intramolecular G-quadruplexes transiently embedded in a DNA duplex. Nucleic Acids Research , , dir. {Oxford University Press}
https://dx.doi.org/10.1093/nar/gkab306
Menoret Séverine, Ouisse Laure-Hélène, Tesson Laurent, Delbos Frédéric, Garnier Delphine, Remy Severine, Usal Claire, Concordet Jean-Paul, Giovannangeli Carine, Chenouard Vanessa, Brusselle Lucas, Mérieau Emmanuel, Nerrière-Daguin Véronique, Duteille Franck, Bellier-Waast Frédérique et al., 2018 — Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models. Transplantation vol. 102, n° 8, dir. {Lippincott, Williams \& Wilkins} p. 1271-1278
https://dx.doi.org/10.1097/TP.0000000000002251
Remy Séverine, Chenouard Vanessa, Tesson Laurent, Usal Claire, Ménoret Séverine, Brusselle Lucas, Heslan Jean-Marie, Nguyen Tuan Huan, Bellien Jeremy, Merot Jean, De Cian Anne, Giovannangeli Carine, Concordet Jean-Paul & Anegon Ignacio, November 2017 — Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group} p. 16554
https://dx.doi.org/10.1038/s41598-017-16328-y
Tesson Laurent, Remy Severine, Ménoret Séverine, Usal Claire, Thinard Reynald, Savignard Chloé, de Cian Anne, Giovannangeli Carine, Concordet Jean-Paul & Anegon Ignacio, 2016 — « Genome Editing in Rats Using TALE Nucleases » in TALENs. Methods in Molecular Biology.. , , p. 245-259
https://dx.doi.org/10.1007/978-1-4939-2932-0_18
Duroux-Richard Isabelle, Giovannangeli Carine & Apparailly Florence, January 2017 — CRISPR-Cas9: A revolution in genome editing in rheumatic diseases. Joint Bone Spine vol. 84, n° 1, dir. {Elsevier Masson} p. 1-4
https://dx.doi.org/10.1016/j.jbspin.2016.09.012
Renaud Jean-Baptiste, Boix Charlotte, Charpentier Marine, deCian Anne, Cochennec Julien, Duvernois-Berthet Evelyne, Perrouault Loïc, Tesson Laurent, Edouard Joanne, Thinard Reynald, Cherifi Yacine, Menoret Séverine, Fontanière Sandra, de Crozé Noémie, Fraichard Alexandre et al., March 2016 — Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases.. Cell Reports vol. 14, n° 9, dir. {Elsevier Inc} p. 2263-72
https://dx.doi.org/10.1016/j.celrep.2016.02.018
Solé Anna, Delagoutte Emmanuelle, Ciudad Carlos, Noé Véronique & Alberti Patrizia, February 2017 — Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/srep39898
Audry Julien, Maestroni Laetitia, Delagoutte Emmanuelle, Gauthier Tiphaine, Nakamura Toru, Gachet Yannick, Saintomé Carole, Geli Vincent & Coulon Stephane, 2015 — RPA prevents G-rich structure formation at lagging- strand telomeres to allow maintenance of chromosome ends. EMBO Journal vol. 34, , dir. {EMBO Press} p. 1942-1958
https://dx.doi.org/10.15252/embj.201490773
Larcher Thibaut, Lafoux Aude, Tesson Laurent, Remy Severine, Thepenier Virginie, François Virginie, Le Guiner Caroline, Goubin Hélicia, Dutilleul Maeva, Guigand Lydie, Toumaniantz Gilles, de Cian Anne, Boix Charlotte, Renaud Jean-Baptiste, Cherel Yan et al., 2014 — Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy. PLoS ONE vol. 9, n° 10, dir. {Public Library of Science} 13 p.
https://dx.doi.org/10.1371/journal.pone.0110371
Roulon Thibaut, Le Cam Eric & Escudé Christophe, June 2006 — A New Supramolecular Structure Made of Two Different Plasmids Linked by a Circular Oligonucleotide. ChemBioChem vol. 7, n° 6, dir. {Wiley-VCH Verlag} p. 912-915
https://dx.doi.org/10.1002/cbic.200500478
Rakkaa Tarik, Escudé Christophe, Giet Régis, Magnaghi-Jaulin Laura & Jaulin Christian, 2014 — CDK11p58 kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis. Chromosome Research vol. 22, n° 3, dir. {Springer Verlag} p. 267-276
https://dx.doi.org/10.1007/s10577-013-9400-x
Geinguenaud Frédéric, Calandrini Vania, Teixeira José, Mayer Claudine, Liquier Jean, Lavelle Christophe & Arluison Véronique, January 2011 — Conformational transition of DNA bound to Hfq probed by infrared spectroscopy.. Physical Chemistry Chemical Physics vol. 13, n° 3, dir. {Royal Society of Chemistry} p. 1222-9
https://dx.doi.org/10.1039/c0cp01084g
Lavelle Christophe, Berry Hugues, Beslon Guillaume, Ginelli Francisco, Giavitto Jean-Louis, Kapoula Zoi, Le Bivic André, Peyriéras Nadine, Radulescu Ovidiu, Six Adrien, Thomas-Vaslin Véronique & Bourgine Paul, 2008 — From Molecules to Organisms: Towards Multiscale Integrated Models of Biological Systems. Theoretical Biology Insights vol. 1, , dir. {Libertas Academica Ltd} p. 13-22
https://hal.inria.fr/inria-00331281
Lavelle Christophe, 2019 — « La formulation en cuisine : entre chimie et alchimie ou la maitrise des molécules » in Les métamorphoses de l’aliment.. , ,
https://hal.archives-ouvertes.fr/hal-03009758
Recouvreux Pierre, Lavelle Christophe, Barbi Maria, Conde e Silva Natalia, Le Cam Eric, Victor Jean-Marc & Viovy Jean-Louis, June 2011 — Linker Histones Incorporation Maintains Chromatin Fiber Plasticity. Biophysical Journal vol. 100, n° 11, dir. {Biophysical Society} p. 2726-2735
https://dx.doi.org/10.1016/j.bpj.2011.03.064
Lavelle Christophe, Praly Elise, Bensimon David, Le Cam Eric & Croquette Vincent, October 2011 — Nucleosome-remodelling machines and other molecular motors observed at the single-molecule level. FEBS Journal vol. 278, n° 19, dir. {Wiley} p. 3596-3607
https://dx.doi.org/10.1111/j.1742-4658.2011.08280.x
Lavelle Christophe, 2019 — « Cuisiner/pâtisser avec le chocolat : jeux de textures » in Les goûts du chocolat dans le monde.. , ,
https://hal.archives-ouvertes.fr/hal-03009787
Ribeyre Cyril, Lopes Judith, Boulé Jean-Baptiste, Piazza Aurele, Guédin Aurore, Zakian Virginia, Mergny Jean-Louis & Nicolas Alain, 2009 — The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo. PLoS Genetics vol. 5, n° 5, dir. {Public Library of Science} e1000475
https://dx.doi.org/10.1371/journal.pgen.1000475
Rouis Oumayma, Broussard Cedric, Guillonneau Francois, Boulé Jean-Baptiste & Delagoutte Emmanuelle, January 2020 — Identification of hemicatenane-specific binding proteins by fractionation of Hela nuclei extracts. Biochemical Journal vol. 477, n° 2, dir. {Portland Press} p. 509-524
https://dx.doi.org/10.1042/BCJ20190855
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