AASPE is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
List of publications
, July 2021 — Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability. Epigenetics
& Chromatin. Vol. 14, n° 1, dir. BioMed Central.
, December 2021 — « Tagging Proteins with Fluorescent Reporters Using the CRISPR/Cas9 System and Double-Stranded DNA Donors » in Multiprotein Complexes. P. 39-57.
, March 2021 — Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish. eLife. Vol. 10, dir. eLife Sciences Publication.
, 2020 — AP-TSS: A New Method for the Analysis of RNA Expression from Particular and Challenging Transcription Start Sites. Biomolecules. Vol. 10, n° 6, dir. MDPI, p. 827.
, March 2020 — Editing a y-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype. Science Advances. Vol. 6, n° 7, dir. American Association for the Advancement of Science (AAAS), eaay9392.
, March 2019 — Edition of TFAM gene by CRISPR/Cas9 technology in bovine model. PLoS ONE. Vol. 14, n° 3, dir. Public Library of Science, e0213376.
, 2019 — Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells. PLoS Genetics. Vol. 15, n° 10, dir. Public Library of Science, e1008355.
, March 2019 — Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA). Molecules. Vol. 24, n° 3, dir. MDPI, p. 577.
, March 2019 — UCP1 transrepression in Brown Fat in vivo and mineralocorticoid receptor anti-thermogenic effects. Annales d’Endocrinologie. Vol. 80, n° 1, dir. Elsevier Masson, p. 1-9.
, June 2019 — Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. International Journal of Molecular Sciences. Vol. 20, n° 11, dir. MDPI, p. 2791.
, 2018 — Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells. iScience. Vol. 5, dir. Elsevier, p. 19-29.
, 2018 — Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models. Transplantation. Vol. 102, n° 8, dir. Lippincott, Williams \& Wilkins, p. 1271-1278.
, December 2018 — High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion. Scientific Reports. Vol. 8, n° 1, dir. Nature Publishing Group.
, December 2017 — HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis. Scientific Reports. Vol. 7, n° 1, dir. Nature Publishing Group, p. 4835.
, December 2017 — RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity. Cellular and Molecular Life Sciences. Vol. 74, n° 24, dir. Springer Verlag, p. 4587-4597.
, November 2017 — Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation. Scientific Reports. Vol. 7, n° 1, dir. Nature Publishing Group, p. 16554.
, April 2017 — Neu5Gc and \alpha1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs. Diabetes. Vol. 66, n° 4, dir. American Diabetes Association, 987-993..
, July 2016 — Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.. Genome Biology. Vol. 17, n° 1, dir. BioMed Central, p. 148.
, December 2016 — The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1. Molecular Biology of the Cell. Vol. 27, n° 24, dir. American Society for Cell Biology, p. 3841-3854.
, March 2016 — Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases.. Cell Reports. Vol. 14, n° 9, dir. Elsevier Inc, p. 2263-72.