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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Geny Sylvain, Pichard Simon, Brion Alice, Renaud Jean-Baptiste, Jacquemin Sophie, Concordet Jean-Paul & Poterszman A., December 2021 — « Tagging Proteins with Fluorescent Reporters Using the CRISPR/Cas9 System and Double-Stranded DNA Donors » in Multiprotein Complexes.. , , p. 39-57
https://dx.doi.org/10.1007/978-1-0716-1126-5_3
Pipier A., Devaux A., Lavergne T., Adrait A., Couté Y., Britton S., Calsou P., Riou J., Defrancq E. & Gomez D., December 2021 — Constrained G4 structures unveil topology specificity of known and new G4 binding proteins. Scientific Reports vol. 11, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/s41598-021-92806-8
Roger Lauréline, Tomas Fanny & Gire Véronique, December 2021 — Mechanisms and Regulation of Cellular Senescence. International Journal of Molecular Sciences vol. 22, n° 23, dir. {MDPI} p. 13173
https://dx.doi.org/10.3390/ijms222313173
Ho Shu, Lajaunie Rebecca, Lerat Marion, Le Mickael, Crépel Valérie, Loulier Karine, Livet Jean, Kessler Jean-Pierre & Marcaggi Païkan, November 2021 — A stable proportion of Purkinje cell inputs from parallel fibers are silent during cerebellar maturation. Proceedings of the National Academy of Sciences of the United States of America vol. 118, n° 45, e2024890118
https://dx.doi.org/10.1073/pnas.2024890118
HAL ID
hal-04981514
Amendola Mario, Bedel Aurélie, Buj-Bello Ana, Carrara Mathieu, Concordet Jean-Paul, Frati Giacomo, Gilot David, Giovannangeli Carine, Gutierrez-Guerrero Alejandra, Laurent Marine, Miccio Annarita, Moreau-Gaudry François, Sourd Célia, Valton Julien & Verhoeyen Els, October 2021 — Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Human Gene Therapy vol. 32, 19-20, dir. {Mary Ann Liebert} p. 1059-1075
https://dx.doi.org/10.1089/hum.2021.191
Sole Anna, Grossetête Sandrine, Heintzé Maxime, Babin Loelia, Zaïdi Sakina, Revy Patrick, Renouf Benjamin, deCian Anne, Giovannangeli Carine, Pierre-Eugène Cécile, Janoueix-Lerosey Isabelle, Couronné Lucile, Kaltenbach Sophie, Tomishima Mark, Jasin Maria et al., October 2021 — Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells. Cancer Research vol. 81, n° 19, dir. {American Association for Cancer Research} p. 4994-5006
https://dx.doi.org/10.1158/0008-5472.CAN-20-3837
Sun Jian-Sheng, October 2021 — « L’interdépendance des vivants et le concept One Health (une seule santé) : l’exemple de l’émergence du virus Nipah » in Quel futur pour le vivant ?.. , , dir. {Editions de l'aube} p. 103-111
https://hal-mnhn.archives-ouvertes.fr/mnhn-03890896
Chatain Jean, Hatem Georges, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
https://dx.doi.org/10.1093/nar/gkab768
Roldán Édgar, Barral Jérémie, Martin Pascal, Parrondo Juan & Jülicher Frank, August 2021 — Quantifying entropy production in active fluctuations of the hair-cell bundle from time irreversibility and uncertainty relations. New Journal of Physics vol. 23, n° 8, dir. {Institute of Physics: Open Access Journals} p. 083013
https://dx.doi.org/10.1088/1367-2630/ac0f18
Haschka Thomas, Baptiste Morlot Jean, Carron Leopold & Mozziconacci Julien, July 2021 — Improving distance measures between genomic tracks with mutual proximity. Briefings in Bioinformatics , , dir. {Oxford University Press (OUP)}
https://dx.doi.org/10.1093/bib/bbab266
Decombe Sheldon, Loll François, Caccianini Laura, Affannoukoué Kévin, Izeddin Ignacio, Mozziconacci Julien, Escudé Christophe & Lopes Judith, July 2021 — Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability. Epigenetics & Chromatin vol. 14, n° 1, dir. {BioMed Central}
https://dx.doi.org/10.1186/s13072-021-00410-x
Chatain Jean, Blond Alain, Phan Anh Tuân, Saintomé Carole & Alberti Patrizia, July 2021 — GGGCTA repeats can fold into hairpins poorly unfolded by replication protein A: a possible origin of the length-dependent instability of GGGCTA variant repeats in human telomeres. Nucleic Acids Research , , dir. {Oxford University Press}
https://dx.doi.org/10.1093/nar/gkab518
Decombe Sheldon, Loll François, Caccianini Laura, Affannoukoué Kévin, Izeddin Ignacio, Mozziconacci Julien, Escudé Christophe & Lopes Judith, July 2021 — Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability. Epigenetics & Chromatin vol. 14, n° 1,
https://dx.doi.org/10.1186/s13072-021-00410-x
HAL ID
hal-03336457
Bossaert Madeleine, Pipier Angélique, Riou Jean-Francois, Noirot Céline, Nguyễn Linh-Trang, Serre Remy-Felix, Bouchez Olivier, Defrancq Eric, Calsou Patrick, Britton Sébastien & Gomez Dennis, June 2021 — Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands. G-quadruplexes (G4) are non-canonical DNA structures found in the genome of most species including human. Small molecules… eLife vol. 10, , dir. eLife Sciences Publications, Ltd e65184
ISSN
2050-084X
https://dx.doi.org/10.7554/eLife.65184
Haschka Thomas, Ponger Loic, Escude Christophe & Mozziconacci Julien, June 2021 — MNHN-Tree-Tools: A toolbox for tree inference using multi-scale clustering of a set of sequences. Bioinformatics , , dir. {Oxford University Press (OUP)}
https://dx.doi.org/10.1093/bioinformatics/btab430
Lavelle Christophe & Boulé Jean-Baptiste, June 2021 — Fermentation: A Short Scientific and Culinary Overview of Kefir. , ,
https://hal.archives-ouvertes.fr/hal-03320166
Ribeiro Jonathan, Dupaigne Pauline, Petrillo Cynthia, Ducrot Cécile, Duquenne Clotilde, Veaute Xavier, Saintomé Carole, Busso Didier, Guerois Raphaël, Martini Emmanuelle & Livera Gabriel, June 2021 — The meiosis-specific MEIOB–SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex. DNA Repair vol. 102, , p. 103097
https://dx.doi.org/10.1016/j.dnarep.2021.103097
Gurung Pratima, Gomes Ana Rita, Martins Rafael, Juranek Stefan, Alberti Patrizia, Mbang-Benet Diane-Ethna, Urbach S, Gazanion Elodie, Guitard Vincent, Paeschke Katrin & Lopez-Rubio José Juan, April 2021 — PfGBP2 is a novel G-quadruplex binding protein in Plasmodium falciparum. Cellular Microbiology vol. 23, n° 4, dir. {Wiley} e13303
https://dx.doi.org/10.1111/cmi.13303
Routhier Etienne, Pierre Edgard, Khodabandelou Ghazaleh & Mozziconacci Julien, March 2021 — Genome-wide prediction of DNA mutation effect on nucleosome positions for yeast synthetic genomics. Genome Research vol. 31, n° 2, dir. {Cold Spring Harbor Laboratory Press} p. 317-326
https://dx.doi.org/10.1101/gr.264416.120
Pavani Giulia, Fabiano Anna, Laurent Marine, Amor Fatima, Cantelli Erika, Chalumeau Anne, Maule Giulia, Tachtsidi Alexandra, Concordet Jean-Paul, Cereseto Anna, Mavilio Fulvio, Ferrari Giuliana, Miccio Annarita & Amendola Mario, March 2021 — Correction of \beta-thalassemia by CRISPR/Cas9 editing of the \alpha-globin locus in human hematopoietic stem cells. Blood Advances vol. 5, n° 5, dir. {The American Society of Hematology} p. 1137-1153
https://dx.doi.org/10.1182/bloodadvances.2020001996
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  • Patrizia ALBERTI
  • Jean-Baptiste BOULÉ
  • Alice BRION
  • Jean-Paul CONCORDET
  • Emmanuelle DELAGOUTTE
  • Christophe ESCUDÉ
  • Carine GIOVANNANGELI
  • Alexandra JOUBERT
  • Christophe LAVELLE
  • Judith LOPES
  • Païkan MARCAGGI
  • Julien MOZZICONACCI
  • Loïc PONGER
  • Lauréline ROGER
  • Carole SAINTOMÉ
  • Jian-Sheng SUN

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  • (-) 2021

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  • Équipe ARChE
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