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Institutional affiliations MNHN - CNRS - Inserm - SU
Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • GE2R _ Genome Editing, DNA double-strand break Repair and cellular Responses
    • SANTE_Structure of Nucleic Acids, Telomeres and Evolution
    • ARChE _ ADN Repeated, Chromatin, Evolution
    • GPA_Genomics and Physiology of Adaptation
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Generalizing and improving the use of enhanced bioluminescent reporting systems

Evolution of telomeres

Telomeric dysfunctions

Enhancing bioluminescent reporting systems

Expanding the tools to interfere with telomere regulation through epigenetic, new small ligands and AsiDNA

Fishing G4-interacting proteins

test FR

vn,bnc

Non-canonical nucleic acid structures and interactions with proteins

Understanding how single-stranded DNA binding proteins acting at telomeres deal with the DNA secondary structures that can form at telomeres

CEMIM Imaging Platform
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HEK293_GFP_tacgene_©alice.brion

TACGENE

TACGENE was created in 2011 within U1154–UMR7196, to facilitate the access of academic laboratories to genome editing techniques.
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fibroblast_©VSHYUKOVA / SCIENCE PHOTO LIBRARY

Research team

The Unit is composed of 4 teams.
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G4_ G quadruplexes

SANTE

Structure of Nucleic Acids, Telomeres and Evolution

Pôle imagerie

SERVICE COMMUN D'IMAGERIE
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offre emploi_©urologue-paris-messas.fr

Internship offer, theses and post-doctoral

Here are the offers of internships, theses and post-doctorates to be filled within the unit.
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Transformation de l'ADN

Presentation

Structure et Instabilité des Génomes
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©freepik_ensemble-equipements-scientifiques_1308-34259

Equipment

The equipment present in the laboratory.

Scientific life / external seminars

à faire

Theses and HDR

The theses and HDR that took place in the laboratory as well as those to come.

 

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The publications of the whole unit.
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  • Research teams
    • GE2R
    • SANTÉ
    • ARChE
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  • Resources / common services
    • TACGENE
    • Equipment
  • Scientific life / external seminars
    • External seminars
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