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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Safa Layal, Gueddouda Nassima Meriem, Thiébaut Frédéric, Delagoutte Emmanuelle, Petruseva Irina, Lavrik Olga, Mendoza Oscar, Bourdoncle Anne, Alberti Patrizia, Riou Jean-François & Saintomé Carole, 2016 — 5’ to 3’ Unfolding Directionality of DNA Secondary Structures by Replication Protein A. Journal of Biological Chemistry vol. 291, n° 40, dir. {American Society for Biochemistry and Molecular Biology} p. 21246-21256
https://dx.doi.org/10.1074/jbc.M115.709667
Solé Anna, Delagoutte Emmanuelle, Ciudad Carlos, Noé Véronique & Alberti Patrizia, February 2017 — Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/srep39898
Chatain Jean, Hatem Georges, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
https://dx.doi.org/10.1093/nar/gkab768
Anoud M., Delagoutte Emmanuelle, Helleu Quentin, Brion A., Duvernois-Berthet Evelyne, As M., Marques X., Lamribet K., Senamaud C., Jourdren L., Adrait A., Heinrich S., Toutirais G., Hamlaoui S., Gropplero G. et al., January 2024 — Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiation. eLife , ,
https://dx.doi.org/10.7554/eLife.92621.1
Lancrey Astrid, Safa Layal, Chatain Jean, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, March 2018 — The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units. Biochimie vol. 146, , dir. {Elsevier} p. 68-72
https://dx.doi.org/10.1016/j.biochi.2017.11.017
Safa Layal, Delagoutte Emmanuelle, Petruseva Irina, Alberti Patrizia, Lavrik Olga, Riou Jean-François & Saintomé Carole, August 2014 — Binding polarity of RPA to telomeric sequences and influence of G-quadruplex stability. Biochimie vol. 103, , p. 80-88
https://dx.doi.org/10.1016/j.biochi.2014.04.006
Anoud Marwan, Delagoutte Emmanuelle, Helleu Quentin, Brion Alice, Duvernois-Berthet Evelyne, As Marie, Marques Xavier, Lamribet Khadija, Senamaud-Beaufort Catherine, Jourdren Laurent & others, 2024 — Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiation. Elife vol. 13, , RP92621
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By authors

  • Patrizia ALBERTI
  • Alice BRION
  • Jean-Paul CONCORDET
  • Anne DE CIAN
  • Evelyne DUVERNOIS
  • Carine GIOVANNANGELI
  • Quentin HELLEU
  • Khadija LAMRIBET
  • Xavier MARQUES
  • Loïc PONGER
  • Carole SAINTOMÉ
  • (-) Emmanuelle DELAGOUTTE

Year

  • 2024
  • 2021
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  • 2016
  • 2014

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  • Équipe ARChE
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  • Équipe SANTÉ

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  • CNRS
  • INSERM
  • Sorbonne Université
  • (-) MNHN

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