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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Larcher Thibaut, Lafoux Aude, Tesson Laurent, Remy Severine, Thepenier Virginie, François Virginie, Le Guiner Caroline, Goubin Hélicia, Dutilleul Maeva, Guigand Lydie, Toumaniantz Gilles, de Cian Anne, Boix Charlotte, Renaud Jean-Baptiste, Cherel Yan et al., 2014 — Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy. PLoS ONE vol. 9, n° 10, dir. {Public Library of Science} 13 p.
https://dx.doi.org/10.1371/journal.pone.0110371
Sole Anna, Grossetête Sandrine, Heintzé Maxime, Babin Loelia, Zaïdi Sakina, Revy Patrick, Renouf Benjamin, deCian Anne, Giovannangeli Carine, Pierre-Eugène Cécile, Janoueix-Lerosey Isabelle, Couronné Lucile, Kaltenbach Sophie, Tomishima Mark, Jasin Maria et al., October 2021 — Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells. Cancer Research vol. 81, n° 19, dir. {American Association for Cancer Research} p. 4994-5006
https://dx.doi.org/10.1158/0008-5472.CAN-20-3837
Charpentier M., Khedher A. H y, Menoret S., Brion A., Lamribet K., Dardillac E., Boix C., Perrouault L., Tesson L., Geny S., de Cian A., Itier J M, Anegon I., Lopez B., Giovannangeli C. et al., 2018 — CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair. Nature Communications vol. 9, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/s41467-018-03475-7
Amendola Mario, Bedel Aurélie, Buj-Bello Ana, Carrara Mathieu, Concordet Jean-Paul, Frati Giacomo, Gilot David, Giovannangeli Carine, Gutierrez-Guerrero Alejandra, Laurent Marine, Miccio Annarita, Moreau-Gaudry François, Sourd Célia, Valton Julien & Verhoeyen Els, October 2021 — Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Human Gene Therapy vol. 32, 19-20, dir. {Mary Ann Liebert} p. 1059-1075
https://dx.doi.org/10.1089/hum.2021.191
de Cian Anne, Praly Elise, Ding Fangyuan, Singh Vijender, Lavelle Christophe, Le Cam Eric, Croquette Vincent, Pietrement Olivier & Bensimon David, February 2012 — ATP-Independent Cooperative Binding of Yeast Isw1a to Bare and Nucleosomal DNA. PLoS ONE vol. 7, n° 2, dir. {Public Library of Science} e31845
https://dx.doi.org/10.1371/journal.pone.0031845
Ménoret Séverine, Ouisse Laure-Hélène, Tesson L., Remy S., Usal Claire, Concordet J.-P., Giovannangeli C., Chenouard Vanessa, Brusselle L., Merieau E., Daguin Véronique, Duteille F., Bellier-Waast Frédérique, Fraichard A. & Anegon Ignacio, April 2018 — Generation of Rag1 and Il2rg immunodeficient rats and application to humanization studies. , , Poster
https://www.hal.inserm.fr/inserm-02160389
Anoud M., Delagoutte Emmanuelle, Helleu Quentin, Brion A., Duvernois-Berthet Evelyne, As M., Marques X., Lamribet K., Senamaud C., Jourdren L., Adrait A., Heinrich S., Toutirais G., Hamlaoui S., Gropplero G. et al., January 2024 — Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiation. eLife , ,
https://dx.doi.org/10.7554/eLife.92621.1
Antoniou Panagiotis, Hardouin Giulia, Martinucci Pierre, Frati Giacomo, Felix Tristan, Chalumeau Anne, Fontana Letizia, Martin Jeanne, Masson Cecile, Brusson Megane, Maule Giulia, Rosello Marion, Giovannangeli Carine, Abramowski Vincent, de Villartay Jean-Pierre et al., November 2022 — Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression. Nature Communications vol. 13, n° 1, p. 6618
https://dx.doi.org/10.1038/s41467-022-34493-1
Babin Loélia, Darchen Alice, Robert Elie, Aid Zakia, Borry Rosalie, Soudais Claire, Piganeau Marion, de Cian Anne, Giovannangeli Carine, Bawa Olivia, Rigaud Charlotte, Scoazec Jean-Yves, Couronné Lucile, Veleanu Layla, Cieslak Agata et al., December 2022 — De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells. Molecular Cancer vol. 21, n° 1, dir. {BioMed Central} p. 65
https://dx.doi.org/10.1186/s12943-022-01520-0
Rosello Marion, Serafini Malo, Mignani Luca, Finazzi Dario, Giovannangeli Carine, Mione Marina C, Concordet Jean-Paul & del Bene Filippo, June 2022 — Disease modeling by efficient genome editing using a near PAM-less base editor in vivo. Nature Communications vol. 13, n° 1, dir. {Nature Publishing Group} p. 3435
https://dx.doi.org/10.1038/s41467-022-31172-z
Anoud Marwan, Delagoutte Emmanuelle, Helleu Quentin, Brion Alice, Duvernois-Berthet Evelyne, As Marie, Marques Xavier, Lamribet Khadija, Senamaud-Beaufort Catherine, Jourdren Laurent & others, 2024 — Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiation. Elife vol. 13, , RP92621
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  • Patrizia ALBERTI
  • Charlotte BOIX
  • Jean-Baptiste BOULÉ
  • Alice BRION
  • Jean-Paul CONCORDET
  • Anne DE CIAN
  • Emmanuelle DELAGOUTTE
  • Evelyne DUVERNOIS
  • Carine GIOVANNANGELI
  • Quentin HELLEU
  • Khadija LAMRIBET
  • Christophe LAVELLE
  • Xavier MARQUES
  • Loïc PONGER

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