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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • GE2R _ Genome Editing, DNA double-strand break Repair and cellular Responses
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Antoniou Panagiotis, Hardouin Giulia, Martinucci Pierre, Frati Giacomo, Felix Tristan, Chalumeau Anne, Fontana Letizia, Martin Jeanne, Masson Cecile, Brusson Megane, Maule Giulia, Rosello Marion, Giovannangeli Carine, Abramowski Vincent, de Villartay Jean-Pierre et al., November 2022 — Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression. Nature Communications vol. 13, n° 1, p. 6618
https://dx.doi.org/10.1038/s41467-022-34493-1
Babin Loélia, Darchen Alice, Robert Elie, Aid Zakia, Borry Rosalie, Soudais Claire, Piganeau Marion, de Cian Anne, Giovannangeli Carine, Bawa Olivia, Rigaud Charlotte, Scoazec Jean-Yves, Couronné Lucile, Veleanu Layla, Cieslak Agata et al., December 2022 — De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells. Molecular Cancer vol. 21, n° 1, dir. {BioMed Central} p. 65
https://dx.doi.org/10.1186/s12943-022-01520-0
Rosello Marion, Serafini Malo, Mignani Luca, Finazzi Dario, Giovannangeli Carine, Mione Marina C, Concordet Jean-Paul & del Bene Filippo, June 2022 — Disease modeling by efficient genome editing using a near PAM-less base editor in vivo. Nature Communications vol. 13, n° 1, dir. {Nature Publishing Group} p. 3435
https://dx.doi.org/10.1038/s41467-022-31172-z
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  • Jean-Paul CONCORDET
  • Anne DE CIAN
  • Carine GIOVANNANGELI

Year

  • (-) 2022

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  • (-) Équipe GE2R

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  • INSERM
  • (-) CNRS

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A research group
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