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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
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Romiguier Jonathan, Borowiec Marek L, Weyna Arthur, Helleu Quentin, Loire Etienne, La Mendola Christine, Rabeling Christian, Fisher Brian L, Ward Philip S & Keller Laurent, 2022 — Ant phylogenomics reveals a natural selection hotspot preceding the origin of complex eusociality. Current Biology vol. 32, n° 13, p. 2942-2947
Kermasson Laëtitia, Churikov Dmitri, Awad Aya, Smoom Riham, Lainey Elodie, Touzot Fabien, Audebert-Bellanger Séverine, Haro Sophie, Roger Laureline, Costa Emilia, Mouf Maload, Bottero Adriana Jorgelina, Oleastro Matias, Abdo Chrystelle, de Villartay Jean-Pierre et al., January 2022 — Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects. Blood , ,
https://dx.doi.org/10.1182/blood.2021010791
Antoniou Panagiotis, Hardouin Giulia, Martinucci Pierre, Frati Giacomo, Felix Tristan, Chalumeau Anne, Fontana Letizia, Martin Jeanne, Masson Cecile, Brusson Megane, Maule Giulia, Rosello Marion, Giovannangeli Carine, Abramowski Vincent, de Villartay Jean-Pierre et al., November 2022 — Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression. Nature Communications vol. 13, n° 1, p. 6618
https://dx.doi.org/10.1038/s41467-022-34493-1
Frank Erik T, Kesner Lucie, Liberti Joanito, Helleu Quentin, LeBoeuf Adria C, Dascalu Andrei, Sponsler Douglas B, Azuma Fumika, Economo Evan P, Waridel Patrice & others, 2022 — Antimicrobial wound care in an ant society. BioRxiv , , p. 2022-04
Helleu Quentin, Roux Camille, Ross Kenneth G & Keller Laurent, 2022 — Radiation and hybridization underpin the spread of the fire ant social supergene. Proceedings of the National Academy of Sciences vol. 119, n° 34, e2201040119
Babin Loélia, Darchen Alice, Robert Elie, Aid Zakia, Borry Rosalie, Soudais Claire, Piganeau Marion, de Cian Anne, Giovannangeli Carine, Bawa Olivia, Rigaud Charlotte, Scoazec Jean-Yves, Couronné Lucile, Veleanu Layla, Cieslak Agata et al., December 2022 — De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells. Molecular Cancer vol. 21, n° 1, dir. {BioMed Central} p. 65
https://dx.doi.org/10.1186/s12943-022-01520-0
Kay Tomas, Helleu Quentin & Keller Laurent, August 2022 — Iterative evolution of supergene-based social polymorphism in ants. Philosophical Transactions of the Royal Society B vol. 377, n° 1856, dir. {Royal Society, The} p. 20210196
https://dx.doi.org/10.1098/rstb.2021.0196
Rosello Marion, Serafini Malo, Mignani Luca, Finazzi Dario, Giovannangeli Carine, Mione Marina C, Concordet Jean-Paul & del Bene Filippo, June 2022 — Disease modeling by efficient genome editing using a near PAM-less base editor in vivo. Nature Communications vol. 13, n° 1, dir. {Nature Publishing Group} p. 3435
https://dx.doi.org/10.1038/s41467-022-31172-z
Mérien Antoine, Tahraoui-Bories Julie, Cailleret Michel, Dupont Jean-Baptiste, Leteur Céline, Polentes Jérôme, Carteron Alexandre, Polvèche Hélène, Concordet Jean-Paul, Pinset Christian, Jarrige Margot, Furling Denis & Martinat Cécile, 2022 — CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis. Human Molecular Genetics vol. 31, n° 1, dir. {Oxford University Press (OUP)} p. 41-56
https://dx.doi.org/10.1093/hmg/ddab218
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  • Jean-Paul CONCORDET
  • Anne DE CIAN
  • Carine GIOVANNANGELI
  • Quentin HELLEU
  • Lauréline ROGER

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  • (-) 2022

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  • (-) Équipe GE2R

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  • CNRS
  • INSERM
  • MNHN

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A research group
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