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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Charpentier M., Khedher A. H y, Menoret S., Brion A., Lamribet K., Dardillac E., Boix C., Perrouault L., Tesson L., Geny S., de Cian A., Itier J M, Anegon I., Lopez B., Giovannangeli C. et al., 2018 — CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair. Nature Communications vol. 9, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/s41467-018-03475-7
Torbey Patrick, Thierion Elodie, Collombet Samuel, de Cian Anne, Desmarquet-Trin-Dinh Carole, Dura Mathilde, Concordet Jean-Paul, Charnay Patrick & Gilardi-Hebenstreit Pascale, August 2018 — Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation. PLoS Genetics vol. 14, n° 8, dir. {Public Library of Science} e1007581
https://dx.doi.org/10.1371/journal.pgen.1007581
de Oliveira Vanessa Cristina, Gomes Mariano Junior Clésio, Belizário José Ernesto, Krieger José Eduardo, Fernandes Bressan Fabiana, Roballo Kelly Cristine Santos, Fantinato-Neto Paulo, Meirelles Flávio Vieira, Chiaratti Marcos Roberto, Concordet Jean-Paul & Ambrósio Carlos Eduardo, July 2020 — Characterization of post-edited cells modified in the TFAM gene by CRISPR/Cas9 technology in the bovine model. PLoS ONE vol. 15, n° 7, dir. {Public Library of Science} e0235856
https://dx.doi.org/10.1371/journal.pone.0235856
Mollà-Herman Anahi, Boularan Cédric, Ghossoub Rania, G.H.Scott Mark, Burtey Anne, Zarka Marion, Saunier Sophie, Concordet Jean-Paul, Marullo Stefano & Benmerah Alexandre R., November 2008 — Targeting of \beta-Arrestin2 to the Centrosome and Primary Cilium: Role in Cell Proliferation Control. PLoS ONE vol. 3, n° 11, dir. {Public Library of Science} e3728
https://dx.doi.org/10.1371/journal.pone.0003728
Amendola Mario, Bedel Aurélie, Buj-Bello Ana, Carrara Mathieu, Concordet Jean-Paul, Frati Giacomo, Gilot David, Giovannangeli Carine, Gutierrez-Guerrero Alejandra, Laurent Marine, Miccio Annarita, Moreau-Gaudry François, Sourd Célia, Valton Julien & Verhoeyen Els, October 2021 — Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Human Gene Therapy vol. 32, 19-20, dir. {Mary Ann Liebert} p. 1059-1075
https://dx.doi.org/10.1089/hum.2021.191
de Cian Anne, Praly Elise, Ding Fangyuan, Singh Vijender, Lavelle Christophe, Le Cam Eric, Croquette Vincent, Pietrement Olivier & Bensimon David, February 2012 — ATP-Independent Cooperative Binding of Yeast Isw1a to Bare and Nucleosomal DNA. PLoS ONE vol. 7, n° 2, dir. {Public Library of Science} e31845
https://dx.doi.org/10.1371/journal.pone.0031845
Kanhoush Rasha, Praseuth Danièle, Perrin Caroline, Chardard Dominique, Vinh Joelle & Penrad-Mobayed May, January 2011 — Differential RNA-binding activity of the hnRNP G protein correlated with the sex genotype in the amphibian oocyte.. Nucleic Acids Research , , dir. {Oxford University Press} epub ahead of print
https://dx.doi.org/10.1093/nar/gkq1315
Joutsen Jenny, da Silva Alejandro Jose, Luoto Jens Christian, Budzynski Marek Andrzej, Nylund Anna Serafia, de Thonel Aurélie, Concordet Jean-Paul, Mezger Valérie, Sabéran-Djoneidi Délara, Henriksson Eva & Sistonen Lea, January 2020 — Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion. Cell Reports vol. 30, n° 2, dir. {Elsevier Inc} 583-597.e6
https://dx.doi.org/10.1016/j.celrep.2019.12.037
Bastin-Héline Lucie, de Fouchier Arthur A., Cao Song, Koutroumpa Fotini A., Caballero-Vidal Gabriela, Robakiewicz Stefania, Monsempes Christelle, Franç Marie-Christine, Ribeyre Tatiana, Maria Annick, Chertemps Thomas, de Cian Anne, Ill William B Walker, Wang Guirong, Jacquin-Joly Emmanuelle V et al., December 2019 — A novel lineage of candidate pheromone receptors for sex communication in moths. eLife vol. 8, , dir. {eLife Sciences Publication}
https://dx.doi.org/10.7554/eLife.49826
Pavani Giulia, Laurent Marine, Fabiano Anna, Cantelli Erika, Sakkal Aboud, Corre Guillaume, Lenting Peter J., Concordet Jean-Paul, Toueille Magali, Miccio Annarita & Amendola Mario, July 2020 — Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins. Nature Communications vol. 11, n° 1, dir. {Nature Publishing Group} p. 3778
https://dx.doi.org/10.1038/s41467-020-17552-3
Ménoret Séverine, Ouisse Laure-Hélène, Tesson L., Remy S., Usal Claire, Concordet J.-P., Giovannangeli C., Chenouard Vanessa, Brusselle L., Merieau E., Daguin Véronique, Duteille F., Bellier-Waast Frédérique, Fraichard A. & Anegon Ignacio, April 2018 — Generation of Rag1 and Il2rg immunodeficient rats and application to humanization studies. , , Poster
https://www.hal.inserm.fr/inserm-02160389
Dreano Elise, Bacchetta Marc, Simonin Juliette, Galmiche Louise, Usal Claire, Slimani Lotfi, Sadoine Jérémy, Tesson Laurent, Anegon Ignacio, Concordet Jean-paul, Hatton Aurélie, Vignaud Lucile, Tondelier Danielle, Sermet-gaudelus Isabelle, Chanson Marc et al., November 2019 — Characterization of two rat models of cystic fibrosis-KO and F508del CFTR-Generated by Crispr-Cas9. Animal Model Exp Med / Animal models and experimental medicine. vol. 2, n° 4, dir. {[Hoboken, New Jersey] : John Wiley \& Sons, Inc., [2018]-} p. 297-311
https://dx.doi.org/10.1002/ame2.12091
Pan Qiaowei, Feron Romain, Yano Ayaka, Guyomard René, Jouanno Elodie, Vigouroux Estelle, Wen Ming, Busnel Jean-Mickaël, Bobe Julien, Concordet Jean-Paul, Parrinello Hugues, Journot Laurent, Klopp Christophe C., Lluch Jérôme, Roques Céline et al., August 2019 — Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation. PLoS Genetics vol. 15, n° 8, dir. {Public Library of Science} e1008013
https://dx.doi.org/10.1371/journal.pgen.1008013
Roger Lauréline, Tomas Fanny & Gire Véronique, December 2021 — Mechanisms and Regulation of Cellular Senescence. International Journal of Molecular Sciences vol. 22, n° 23, dir. {MDPI} p. 13173
https://dx.doi.org/10.3390/ijms222313173
Steed Emily, Faggianelli Nathalie, Roth Stephane, Ramspacher Caroline, Concordet Jean-Paul & Vermot Julien, 2016 — klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. Nature Communications vol. 7, , dir. {Nature Publishing Group} p. 11646
https://dx.doi.org/10.1038/ncomms11646
Romiguier Jonathan, Borowiec Marek L, Weyna Arthur, Helleu Quentin, Loire Etienne, La Mendola Christine, Rabeling Christian, Fisher Brian L, Ward Philip S & Keller Laurent, 2022 — Ant phylogenomics reveals a natural selection hotspot preceding the origin of complex eusociality. Current Biology vol. 32, n° 13, p. 2942-2947
Helleu Quentin, Courret Cécile, Ogereau David, Burnham Katie L, Chaminade Nicole, Chakir Mohamed, Aulard Sylvie & Montchamp-Moreau Catherine, 2019 — Sex-Ratio meiotic drive shapes the evolution of the Y chromosome in Drosophila simulans. Molecular Biology and Evolution vol. 36, n° 12, p. 2668-2681
Helleu Quentin, Gérard Pierre R, Dubruille Raphaëlle, Ogereau David, Prud’homme Benjamin, Loppin Benjamin & Montchamp-Moreau Catherine, 2016 — Rapid evolution of a Y-chromosome heterochromatin protein underlies sex chromosome meiotic drive. Proceedings of the National Academy of Sciences vol. 113, n° 15, p. 4110-4115
Helleu Quentin, Gerard Pierre R & Montchamp-Moreau Catherine, 2015 — Sex chromosome drive. Cold Spring Harbor perspectives in biology vol. 7, n° 2, a017616
Doublet Vincent, Helleu Quentin, Raimond Roland, Souty-Grosset Catherine & Marcadé Isabelle, 2013 — Inverted repeats and genome architecture conversions of terrestrial isopods mitochondrial DNA. Journal of molecular evolution vol. 77, , p. 107-118
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  • Patrizia ALBERTI
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