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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Alexandra JOUBERT
Ingénieure d'Étude
alexandra.joubert[at]mnhn.fr
01 40 79 56 64
Équipe GPA

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Christophe LAVELLE
Chargé de recherche
christophe.lavelle[at]mnhn.fr
01 40 79 48 32
Équipe GPA

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Jean-Baptiste BOULÉ
Directeur de Recherche
jean-baptiste.boule[at]mnhn.fr
01 40 79 56 16
Équipe GPA

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Emmanuelle DELAGOUTTE
Chargée de recherche
emmanuelle.delagoutte[at]mnhn.fr
01 40 79 48 32
Équipe GPA

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Fernando LOPES
Ingénieur de Recherche
fernando.lopes [at] mnhn.fr
Équipe GPA

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Lavelle Christophe & Tardin Catherine, October 2019 — Single molecule approaches of nucleic acids conformational changes. Methods vol. 169, , dir. {Elsevier} p. 1-2
https://dx.doi.org/10.1016/j.ymeth.2019.09.009
Bancaud Aurélien, Wagner Gaudeline, Conde E Silva Natalia, Lavelle Christophe, Wong Hua, Mozziconacci Julien, Barbi Maria, Sivolob Andrei, Le Cam Eric, Mouawad Liliane, Viovy Jean-Louis, Victor Jean-Marc & Prunell Ariel, July 2007 — Nucleosome chiral transition under positive torsional stress in single chromatin fibers.. Molecular Cell vol. 27, n° 1, dir. {Elsevier} p. 135-47
https://dx.doi.org/10.1016/j.molcel.2007.05.037
Lavelle Christophe, Bancaud Aurélien, Recouvreux Pierre, Barbi Maria, Victor Jean-Marc & Viovy Jean-Louis, July 2011 — Chromatin topological transitions. Progress of Theoretical Physics Supplement vol. 191, , p. 30-39
https://hal.archives-ouvertes.fr/hal-01053106
Cayrol Bastien, Geinguenaud Frédéric, Lacoste Jérôme, Busi Florent, Le Derout Jacques, PIETREMENT Olivier, Le Cam Eric, Régnier Philippe, Lavelle Christophe & Arluison Véronique, October 2014 — Auto-assembly of E. coli DsrA small noncoding RNA: Molecular characteristics and functional consequences. RNA Biology vol. 6, n° 4, dir. {Taylor \\& Francis} p. 434-445
https://dx.doi.org/10.4161/rna.6.4.8949
Huet Sébastien, Lavelle Christophe, Ranchon Hubert, Carrivain Pascal, Victor Jean-Marc & Bancaud Aurélien, 2014 — Relevance and limitations of crowding, fractal, and polymer models to describe nuclear architecture.. International Review of Cell and Molecular Biology vol. 307, , p. 443-79
https://dx.doi.org/10.1016/B978-0-12-800046-5.00013-8
Lancrey Astrid, Joubert Alexandra & Boulé Jean-Baptiste, May 2018 — Locus specific engineering of tandem DNA repeats in the genome of Saccharomyces cerevisiae using CRISPR/Cas9 and overlapping oligonucleotides. Scientific Reports vol. 8, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/s41598-018-25508-3
Safa Layal, Gueddouda Nassima Meriem, Thiébaut Frédéric, Delagoutte Emmanuelle, Petruseva Irina, Lavrik Olga, Mendoza Oscar, Bourdoncle Anne, Alberti Patrizia, Riou Jean-François & Saintomé Carole, 2016 — 5’ to 3’ Unfolding Directionality of DNA Secondary Structures by Replication Protein A. Journal of Biological Chemistry vol. 291, n° 40, dir. {American Society for Biochemistry and Molecular Biology} p. 21246-21256
https://dx.doi.org/10.1074/jbc.M115.709667
Ménoret Séverine, de Cian Anne, Tesson Laurent, Remy Séverine, Usal Claire, Boulé Jean-Baptiste, Boix Charlotte, Fontanière Sandra, Crénéguy Alison, Nguyen Tuan H., Brusselle Lucas, Thinard Reynald, Gauguier Dominique, Concordet Jean-Paul, Cherifi Yacine et al., October 2015 — Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins. Scientific Reports vol. 5, , dir. {Nature Publishing Group} p. 14410
https://dx.doi.org/10.1038/srep14410
Jiang Kai, Zhang Ce, Guttula Durgarao, Liu Fan, van Kan Jeroen A, Lavelle Christophe, Kubiak Krzysztof, Malabirade Antoine, Lapp Alain, Arluison Véronique & van Der Maarel Johan R C, 2015 — Effects of Hfq on the conformation and compaction of DNA. Nucleic Acids Research vol. 43, n° 8, dir. {Oxford University Press} p. 4332-4341
https://dx.doi.org/10.1093/nar/gkv268
Pina Mery, Basta Tamara, Quax Tessa, Joubert Alexandra, Baconnais Sonia, Cortez Diego, Lambert Sarah, Le Cam Eric, Bell Stephen, Forterre Patrick & Prangishvili David, June 2014 — Unique genome replication mechanism of the archaeal virus AFV1. Molecular Microbiology vol. 92, n° 6, dir. {Wiley} p. 1313-1325
https://dx.doi.org/10.1111/mmi.12630
Ramaen Odile, Joubert Alexandra, Simister Philip, Belgareh-Touzé Naïma, Olivares-Sanchez Maria Conception, Zeeh Jean-Christophe, Chantalat Sophie, Golinelli-Cohen Marie-Pierre, Jackson Catherine L, Biou Valérie & Cherfils Jacqueline, September 2007 — Interactions between conserved domains within homodimers in the BIG1, BIG2, and GBF1 Arf guanine nucleotide exchange factors.. Journal of Biological Chemistry vol. 282, n° 39, dir. {American Society for Biochemistry and Molecular Biology} p. 28834-42
https://dx.doi.org/10.1074/jbc.M705525200
Tran Phong Lan Thao, Rieu Martin, Hodeib Samar, Joubert Alexandra, Ouellet Jimmy, Alberti Patrizia, Bugaut Anthony, Allemand Jean-François, Boulé Jean-Baptiste & Croquette Vincent, 2021 — Folding and persistence times of intramolecular G-quadruplexes transiently embedded in a DNA duplex. Nucleic Acids Research , , dir. {Oxford University Press}
https://dx.doi.org/10.1093/nar/gkab306
Solé Anna, Delagoutte Emmanuelle, Ciudad Carlos, Noé Véronique & Alberti Patrizia, February 2017 — Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/srep39898
Audry Julien, Maestroni Laetitia, Delagoutte Emmanuelle, Gauthier Tiphaine, Nakamura Toru, Gachet Yannick, Saintomé Carole, Geli Vincent & Coulon Stephane, 2015 — RPA prevents G-rich structure formation at lagging- strand telomeres to allow maintenance of chromosome ends. EMBO Journal vol. 34, , dir. {EMBO Press} p. 1942-1958
https://dx.doi.org/10.15252/embj.201490773
Geinguenaud Frédéric, Calandrini Vania, Teixeira José, Mayer Claudine, Liquier Jean, Lavelle Christophe & Arluison Véronique, January 2011 — Conformational transition of DNA bound to Hfq probed by infrared spectroscopy.. Physical Chemistry Chemical Physics vol. 13, n° 3, dir. {Royal Society of Chemistry} p. 1222-9
https://dx.doi.org/10.1039/c0cp01084g
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