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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • GE2R _ Genome Editing, DNA double-strand break Repair and cellular Responses
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Chatain Jean, Hatem Georges, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
https://dx.doi.org/10.1093/nar/gkab768
Chatain Jean, Blond Alain, Phan Anh Tuân, Saintomé Carole & Alberti Patrizia, July 2021 — GGGCTA repeats can fold into hairpins poorly unfolded by replication protein A: a possible origin of the length-dependent instability of GGGCTA variant repeats in human telomeres. Nucleic Acids Research , , dir. {Oxford University Press}
https://dx.doi.org/10.1093/nar/gkab518
De Cian Anne, Guittat Lionel, Kaiser Markus, Saccà Barbara, Amrane Samir, Bourdoncle Anne, Alberti Patrizia, Teulade-Fichou Marie-Paule, Lacroix Laurent & Mergny Jean-Louis, June 2007 — Fluorescence-based melting assays for studying quadruplex ligands.. Methods vol. 42, n° 2, dir. {Elsevier} p. 183-95
https://dx.doi.org/10.1016/j.ymeth.2006.10.004
Bugaut Anthony & Alberti Patrizia, June 2015 — Understanding the stability of DNA G-quadruplex units in long human telomeric strands. Biochimie vol. 113, , dir. {Elsevier} p. 125-133
https://dx.doi.org/10.1016/j.biochi.2015.04.003
Gurung Pratima, Gomes Ana Rita, Martins Rafael, Juranek Stefan, Alberti Patrizia, Mbang-Benet Diane-Ethna, Urbach S, Gazanion Elodie, Guitard Vincent, Paeschke Katrin & Lopez-Rubio José Juan, April 2021 — PfGBP2 is a novel G-quadruplex binding protein in Plasmodium falciparum. Cellular Microbiology vol. 23, n° 4, dir. {Wiley} e13303
https://dx.doi.org/10.1111/cmi.13303
Saintomé C., Alberti Patrizia, Guinot N., Lejault P., Chatain J., Mailliet P., Riou Jean-Francois & Bugaut A., 2018 — Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures. Chemical Communications vol. 54, n° 15, dir. {Royal Society of Chemistry} p. 1897-1900
https://dx.doi.org/10.1039/c7cc07048a
Gazanion Elodie, Lacroix Laurent, Alberti Patrizia, Gurung Pratima, Wein Sharon, Cheng Mingpan, Mergny Jean-louis, Gomes Ana Rita & Lopez‑rubio José‑juan, July 2020 — Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites. PLoS Genetics vol. 16, n° 7, dir. {Public Library of Science} e1008917
https://dx.doi.org/10.1371/journal.pgen.1008917
Lecointre Guillaume, Aish Annabelle, Améziane Nadia, Chekchak Tarik, Goupil Christophe, Grandcolas Philippe, Vincent Julian F V & Sun Jian-Sheng, August 2023 — Revisiting Nature’s “Unifying Patterns”: A Biological Appraisal. Biomimetics vol. 8, n° 4, p. 362
https://dx.doi.org/10.3390/biomimetics8040362
Kochman Rima, Ba Ibrahima, Yates Maı̈lyn, Pirabakaran Vithura, Gourmelon Florian, Churikov Dmitri, Laffaille Marc, Kermasson Laëtitia, Hamelin Coline, Marois Isabelle & others, 2024 — Heterozygous RPA2 variant as a novel genetic cause of telomere biology disorders. Genes & Development vol. 38, 15-16, p. 755-771
Le Berre Gabriel, Hossard Virginie, Riou Jean-Francois & Guieysse-Peugeot Anne-Laure, June 2019 — Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. International Journal of Molecular Sciences vol. 20, n° 11, dir. {MDPI} p. 2791
https://dx.doi.org/10.3390/ijms20112791
Le Berre Gabriel, Hossard Virginie, Riou Jean-Francois & Guieysse-Peugeot Anne-Laure, 2020 — AP-TSS: A New Method for the Analysis of RNA Expression from Particular and Challenging Transcription Start Sites. Biomolecules vol. 10, n° 6, dir. {MDPI} p. 827
https://dx.doi.org/10.3390/biom10060827
Hwang In, Mailliet Patrick, Hossard Virginie, Riou Jean-François, Bugaut Anthony & Roger Lauréline, February 2019 — Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA). Molecules vol. 24, n° 3, dir. {MDPI} p. 577
https://dx.doi.org/10.3390/molecules24030577
Saintomé Carole, Amrane Samir, Mergny Jean-louis & Alberti Patrizia, January 2016 — The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium. Nucleic Acids Research vol. 44, n° 6, dir. {Oxford University Press} p. 2926-2935
https://dx.doi.org/10.1093/nar/gkw003
Lancrey Astrid, Safa Layal, Chatain Jean, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, March 2018 — The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units. Biochimie vol. 146, , dir. {Elsevier} p. 68-72
https://dx.doi.org/10.1016/j.biochi.2017.11.017
Herath Nirmitha, Devun Flavien, Herbette Aurélie, Lienafa Marie-Christine, Chouteau Philippe, Sun Jian-Sheng, Dutreix Marie & Denys Alban, October 2017 — Potentiation of doxorubicin efficacy in hepatocellular carcinoma by the DNA repair inhibitor DT01 in preclinical models. European Radiology vol. 27, n° 10, dir. {Springer Verlag} p. 4435-4444
https://dx.doi.org/10.1007/s00330-017-4792-1
Jdey Wael, Thierry Sylvain, Russo Christophe, Devun Flavien, Al Abo Muthana, Noguiez-Hellin Patricia, Sun Jian-Sheng, Barillot Emmanuel, Zinovyev Andrei, Kuperstein Inna, Pommier Yves & Dutreix Marie, February 2017 — Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP Inhibitors. Clinical Cancer Research vol. 23, n° 4, dir. {American Association for Cancer Research} p. 1001-1011
https://dx.doi.org/10.1158/1078-0432.CCR-16-1193
Herath Nirmitha, Devun Flavien, Lienafa Marie-Christine, Herbette Aurélie, Denys Alban, Sun Jian-Sheng & Dutreix Marie, January 2016 — The DNA Repair Inhibitor DT01 as a Novel Therapeutic Strategy for Chemosensitization of Colorectal Liver Metastasis. Molecular Cancer Therapeutics vol. 15, n° 1, dir. {American Association for Cancer Research} p. 15-22
https://dx.doi.org/10.1158/1535-7163.mct-15-0408
Safa Layal, Delagoutte Emmanuelle, Petruseva Irina, Alberti Patrizia, Lavrik Olga, Riou Jean-François & Saintomé Carole, August 2014 — Binding polarity of RPA to telomeric sequences and influence of G-quadruplex stability. Biochimie vol. 103, , p. 80-88
https://dx.doi.org/10.1016/j.biochi.2014.04.006
Sun Jian-Sheng, June 2022 — « Comment intégrer la DSI (“digital sequence information on genetic ressource”) dans le partage juste et équitable des avantages issus de la biodiversité (CDB) et dans la cadre de la science ouverte (UNESCO) ? » in JFRB2022 : VOUS REPRENDREZ BIEN UN PEU DE CDB ? Un regard de la recherche sur le cadre mondial pour la biodiversité.. , ,
https://hal-mnhn.archives-ouvertes.fr/mnhn-03890907
Sun Jian-Sheng, December 2022 — « PARTAGER LES REVENUS DE LA BIODIVERSITÉ. » in NP-MOP-04 Fourth meeting of the Conference of the Parties serving as the meeting of the Parties to the Nagoya Protocol on Access and Benefit-sharing (Part Two).. , ,
https://hal-mnhn.archives-ouvertes.fr/mnhn-03890884
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  • Patrizia ALBERTI
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