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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
Institutional affiliations MNHN - CNRS - Inserm
Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • ARChE _ ADN Repeated, Chromatin, Evolution
    • GPA_Genomics and Physiology of Adaptation
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Patrizia ALBERTI
Lecturer
patrizia.alberti [at] mnhn.fr
01 40 79 37 27
Équipe SANTÉ

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Gildas MOUTA CARDOSO
Ingénieur d’Étude
gildas.mouta-cardoso [at] mnhn.fr
01 40 79 56 64
Équipe SANTÉ

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Jian-Sheng SUN
Professeur
jian-sheng.sun[at]mnhn.fr
01 40 79 37 26
Équipe SANTÉ

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Anne-Laure GUIEYSSE-PEUGEOT
Professor
anne-laure.guieysse-peugeot[at]mnhn.fr
01 40 79 36 86 / 57 20
Équipe SANTÉ

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Lauréline ROGER
Maîtresse de conférence
laureline.roger [at] mnhn.fr
01 40 79 37 27
Équipe SANTÉ

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

AMRANE Nina
stagiaire
nina.amrane [at] mnhn.fr
01 40 79 38 01
Équipe SANTÉ

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

SALHI Inès
PhD student
ines.salhi [at] mnhn.fr
Équipe SANTÉ

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Marianne Bechara
Doctorante
marianne.bechara [at] mnhn.fr
01 40 79 36 84
Équipe SANTÉ

CNRS UMR 7196 / INSERM U1154

43, rue Cuvier - Case Postale 26

75231 Paris Cedex 05, France

 

Valton Anne-Laure, Hassan-Zadeh Vahideh, Lema Ingrid, Boggetto Nicole, Alberti Patrizia, Saintomé Carole, Riou Jean-Francois & Prioleau Marie-Noëlle, April 2014 — G4 motifs affect origin positioning and efficiency in two vertebrate replicators.. EMBO Journal vol. 33, n° 7, dir. {EMBO Press} p. 732-46
https://dx.doi.org/10.1002/embj.201387506
Safa Layal, Gueddouda Nassima Meriem, Thiébaut Frédéric, Delagoutte Emmanuelle, Petruseva Irina, Lavrik Olga, Mendoza Oscar, Bourdoncle Anne, Alberti Patrizia, Riou Jean-François & Saintomé Carole, 2016 — 5’ to 3’ Unfolding Directionality of DNA Secondary Structures by Replication Protein A. Journal of Biological Chemistry vol. 291, n° 40, dir. {American Society for Biochemistry and Molecular Biology} p. 21246-21256
https://dx.doi.org/10.1074/jbc.M115.709667
Marlin Fanny, Simon Philippe, Bonneau Stéphanie, Alberti Patrizia, Cordier Céline, Boix Charlotte, Perrouault Loïc, Fossey Aurélie, Saison-Behmoaras Tula, Fontecave Marc & Giovannangeli Carine, November 2012 — Flavin Conjugates for Delivery of Peptide Nucleic Acids. ChemBioChem vol. 13, n° 17, dir. {Wiley-VCH Verlag}
https://dx.doi.org/10.1002/cbic.201200505
Tran Phong Lan Thao, Mergny Jean-Louis & Alberti Patrizia, April 2011 — Stability of telomeric G-quadruplexes. Nucleic Acids Research vol. 39, n° 8, dir. {Oxford University Press} p. 3282-3294
https://dx.doi.org/10.1093/nar/gkq1292
de Cian Anne, Grellier Philippe, Mouray Elisabeth, Depoix Delphine, Bertrand Hélène, Monchaud David, Teulade-Fichou Marie-Paule, Mergny Jean-Louis & Alberti Patrizia, November 2008 — Plasmodium Telomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds. ChemBioChem vol. 9, n° 16, dir. {Wiley-VCH Verlag} p. 2730-2739
https://dx.doi.org/10.1002/cbic.200800330
Champion Christine, Guianvarc’H Dominique, Sénamaud-Beaufort Catherine, Jurkowska Renata Z, Jeltsch Albert, Ponger Loïc, Arimondo Paola B & Guieysse-Peugeot Anne-Laure, 2010 — Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.. PLoS ONE vol. 5, n° 8, dir. {Public Library of Science} e12388
https://dx.doi.org/10.1371/journal.pone.0012388
Tran Phong Lan Thao, Rieu Martin, Hodeib Samar, Joubert Alexandra, Ouellet Jimmy, Alberti Patrizia, Bugaut Anthony, Allemand Jean-François, Boulé Jean-Baptiste & Croquette Vincent, 2021 — Folding and persistence times of intramolecular G-quadruplexes transiently embedded in a DNA duplex. Nucleic Acids Research , , dir. {Oxford University Press}
https://dx.doi.org/10.1093/nar/gkab306
Subecz Chloé, Sun Jian-Sheng & Roger Lauréline, February 2021 — Effect of DNA repair inhibitor AsiDNA on the incidence of telomere fusion in crisis. Human Molecular Genetics vol. 30, 3-4, dir. {Oxford University Press (OUP)} p. 172-181
https://dx.doi.org/10.1093/hmg/ddab008
Solé Anna, Delagoutte Emmanuelle, Ciudad Carlos, Noé Véronique & Alberti Patrizia, February 2017 — Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/srep39898
Cordier Céline, Boutimah Fatima, Bourdeloux Mathilde, Dupuy Florian, Met Elisabeth, Alberti Patrizia, Loll François, Chassaing Gérard, Burlina Fabienne & Saison-Behmoaras Tula Ester, August 2014 — Delivery of Antisense Peptide Nucleic Acids to Cells by Conjugation with Small Arginine-Rich Cell-Penetrating Peptide (R/W)9. PLoS ONE vol. 9, n° 8, dir. {Public Library of Science} e104999
https://dx.doi.org/10.1371/journal.pone.0104999
Coquery Nicolas, Pannetier Nicolas, Farion Régine, Herbette Aurélie, Azurmendi Leire, Clarencon Didier, Bauge Stéphane, Josserand Véronique, Rome Claire, Coll Jean-Luc, Sun Jian-Sheng, Barbier Emmanuel L, Dutreix Marie & Rémy ChantalC., 2012 — Distribution and radiosensitizing effect of cholesterol-coupled Dbait molecule in rat model of glioblastoma.. PLoS ONE vol. 7, n° 7, dir. {Public Library of Science} e40567
https://dx.doi.org/10.1371/journal.pone.0040567
Chatain Jean, Hatem Georges, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
https://dx.doi.org/10.1093/nar/gkab768
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  • Patrizia ALBERTI
  • Charlotte BOIX
  • Jean-Baptiste BOULÉ
  • Anne DE CIAN
  • Emmanuelle DELAGOUTTE
  • Carine GIOVANNANGELI
  • Anne-Laure GUIEYSSE-PEUGEOT
  • Virginie HOSSARD
  • Alexandra JOUBERT
  • Patrick MAILLIET
  • Loïc PONGER
  • Lauréline ROGER
  • Carole SAINTOMÉ
  • Jian-Sheng SUN
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  • INSERM
  • Sorbonne Université
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