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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Amendola Mario, Bedel Aurélie, Buj-Bello Ana, Carrara Mathieu, Concordet Jean-Paul, Frati Giacomo, Gilot David, Giovannangeli Carine, Gutierrez-Guerrero Alejandra, Laurent Marine, Miccio Annarita, Moreau-Gaudry François, Sourd Célia, Valton Julien & Verhoeyen Els, October 2021 — Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Human Gene Therapy vol. 32, 19-20, dir. {Mary Ann Liebert} p. 1059-1075
https://dx.doi.org/10.1089/hum.2021.191
Chatain Jean, Hatem Georges, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
https://dx.doi.org/10.1093/nar/gkab768
Decombe Sheldon, Loll François, Caccianini Laura, Affannoukoué Kévin, Izeddin Ignacio, Mozziconacci Julien, Escudé Christophe & Lopes Judith, July 2021 — Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability. Epigenetics & Chromatin vol. 14, n° 1, dir. {BioMed Central}
https://dx.doi.org/10.1186/s13072-021-00410-x
Lavelle Christophe & Boulé Jean-Baptiste, June 2021 — Fermentation: A Short Scientific and Culinary Overview of Kefir. , ,
https://hal.archives-ouvertes.fr/hal-03320166
Haschka Thomas, Ponger Loic, Escude Christophe & Mozziconacci Julien, June 2021 — MNHN-Tree-Tools: A toolbox for tree inference using multi-scale clustering of a set of sequences. Bioinformatics , , dir. {Oxford University Press (OUP)}
https://dx.doi.org/10.1093/bioinformatics/btab430
Tran Phong Lan Thao, Rieu Martin, Hodeib Samar, Joubert Alexandra, Ouellet Jimmy, Alberti Patrizia, Bugaut Anthony, Allemand Jean-François, Boulé Jean-Baptiste & Croquette Vincent, 2021 — Folding and persistence times of intramolecular G-quadruplexes transiently embedded in a DNA duplex. Nucleic Acids Research , , dir. {Oxford University Press}
https://dx.doi.org/10.1093/nar/gkab306
Mitteaux Jérémie, Lejault Pauline, Wojciechowski Filip, Joubert Alexandra, Boudon Julien, Desbois Nicolas, Gros Claude P, Hudson Robert H E, Boulé Jean-Baptiste, Granzhan Anton & Monchaud David, 2021 — Identifying G-Quadruplex-DNA-Disrupting Small Molecules. Journal of the American Chemical Society vol. 143, n° 32, dir. {American Chemical Society} p. 12567-12577
https://dx.doi.org/10.1021/jacs.1c04426
This Vo Kientza Hervé, Kelly Alan L., Burke R. Roisin & Lavelle Christophe, 2021 — « Foreword » in Handbook of Molecular Gastronomy.. , ,
https://hal.inrae.fr/hal-03231908
This Vo Kientza Hervé, Lavelle Christophe, Barbar Reine & Malbec Jean-Marie, 2021 — « An educational satellite project around the scientific elucidation of culinary precisions in Lebanon and in the Middle East » in Handbook of Molecular Gastronomy.. , ,
https://hal.inrae.fr/hal-03232012
This vo Kientza Hervé & Lavelle Christophe, 2021 — « Using liquid nitrogen to prepare ice creams in the restaurant » in Handbook of Molecular Gastronomy.. , ,
https://hal.inrae.fr/hal-03232024
This vo Kientza Hervé & Lavelle Christophe, 2021 — « Food Pairing : is it really about science ? » in Handbook of Molecular Gastronomy.. , ,
https://hal.inrae.fr/hal-03231976
Weber Leslie, Frati Giacomo, Felix Tristan, Hardouin Giulia, Casini Antonio, Wollenschlaeger Clara, Meneghini Vasco, Masson Cecile, de Cian Anne, Chalumeau Anne, Mavilio Fulvio, Amendola Mario, Andre-Schmutz Isabelle, Cereseto Anna, El Nemer Wassim et al., February 2020 — Editing a \gamma-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype. Science Advances vol. 6, n° 7, dir. {American Association for the Advancement of Science (AAAS)} eaay9392
https://dx.doi.org/10.1126/sciadv.aay9392
PIETREMENT Olivier, Arluison Véronique & Lavelle Christophe, February 2020 — « RNA Nanostructure Molecular Imaging » in RNA Spectroscopy.. , , p. 319-327
https://dx.doi.org/10.1007/978-1-0716-0278-2
Rouis Oumayma, Broussard Cedric, Guillonneau Francois, Boulé Jean-Baptiste & Delagoutte Emmanuelle, January 2020 — Identification of hemicatenane-specific binding proteins by fractionation of Hela nuclei extracts. Biochemical Journal vol. 477, n° 2, dir. {Portland Press} p. 509-524
https://dx.doi.org/10.1042/BCJ20190855
Lavelle Christophe & Tardin Catherine, October 2019 — Single molecule approaches of nucleic acids conformational changes. Methods vol. 169, , dir. {Elsevier} p. 1-2
https://dx.doi.org/10.1016/j.ymeth.2019.09.009
Garcin Edwige B, Gon Stéphanie, Sullivan Meghan, Brunette Gregory J, Cian Anne De, Concordet Jean-Paul, Giovannangeli Carine, Dirks Wilhelm G, Eberth Sonja, Bernstein Kara A, Prakash Rohit, Jasin Maria & Modesti Mauro, 2019 — Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells. PLoS Genetics vol. 15, n° 10, dir. {Public Library of Science} e1008355
https://dx.doi.org/10.1371/journal.pgen.1008355
Lavelle Christophe, 2019 — « La formulation en cuisine : entre chimie et alchimie ou la maitrise des molécules » in Les métamorphoses de l’aliment.. , ,
https://hal.archives-ouvertes.fr/hal-03009758
Lavelle Christophe, 2019 — « Cuisiner/pâtisser avec le chocolat : jeux de textures » in Les goûts du chocolat dans le monde.. , ,
https://hal.archives-ouvertes.fr/hal-03009787
Momose Tsuyoshi R, de Cian Anne, Shiba Kogiku, Inaba Kazuo, Giovannangeli Carine & Concordet Jean-Paul, December 2018 — High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion. Scientific Reports vol. 8, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/s41598-018-30188-0
Saintomé Carole & Delagoutte Emmanuelle, August 2018 — Probing hyper-negatively supercoiled mini-circles with nucleases and DNA binding proteins. PLoS ONE vol. 13, n° 8, dir. {Public Library of Science} e0202138
https://dx.doi.org/10.1371/journal.pone.0202138
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