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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Khosravi Mohammad Ali, Abbasalipour Maryam, Concordet Jean-Paul, Berg Johannes Vom, Zeinali Sirous, Arashkia Arash, Azadmanesh Kayhan, Buch Thorsten & Karimipoor Morteza, July 2019 — Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease. European Journal of Pharmacology vol. 854, , dir. {Elsevier} p. 398-405
https://dx.doi.org/10.1016/j.ejphar.2019.04.042
Khosravi Mohammad Ali, Abbasalipour Maryam, Concordet Jean-Paul, Berg Johannes Vom, Zeinali Sirous, Arashkia Arash, Buch Thorsten & Karimipoor Morteza, February 2020 — Expression analysis data of BCL11A and \gamma-globin genes in KU812 and KG-1 cell lines after CRISPR/Cas9-mediated BCL11A enhancer deletion. Data in Brief vol. 28, , dir. {Elsevier} p. 104974
https://dx.doi.org/10.1016/j.dib.2019.104974
De Cian Anne, Cristofari G., Reichenbach P., De Lemos E., Monchaud David, Teulade-Fichou Marie-Paule, Shin-Ya K., Lacroix L., Lingner J. & Mergny Jean-Louis, October 2007 — Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action.. Proceedings of the National Academy of Sciences of the United States of America vol. 104, n° 44, dir. {National Academy of Sciences} p. 17347-52
https://dx.doi.org/10.1073/pnas.0707365104
Lema Ingrid J., Amazit Larbi, Lamribet Khadija, Fagart Jérome, Blanchard Anne, Lombès Marc, Cherradi Nadia & Viengchareun Say, December 2017 — HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group} p. 4835
https://dx.doi.org/10.1038/s41598-017-04838-8
Lema Ingrid J., Amazit Larbi, Lamribet Khadija, Fagart Jérome, Blanchard Anne, Lombès Marc, Cherradi Nadia & Viengchareun Say, December 2017 — RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity. Cellular and Molecular Life Sciences vol. 74, n° 24, dir. {Springer Verlag} p. 4587-4597
https://dx.doi.org/10.1007/s00018-017-2594-x
Viengchareun Say, Lema Ingrid J., Lamribet Khadija, Keo Vixra, Blanchard Anne, Cherradi Nadia & Lombès Marc, September 2014 — Hypertonicity Compromises Renal Mineralocorticoid Receptor Signaling through Tis11b-Mediated Post-Transcriptional Control. Journal of the American Society of Nephrology vol. 25, n° 10, dir. {American Society of Nephrology} p. 2213-2221
https://dx.doi.org/10.1681/ASN.2013091023
Kuhn Emmanuelle, Lamribet Khadija, Viengchareun Say, LeMenuet Damien, Fève Bruno & Lombès Marc, February 2019 — UCP1 transrepression in Brown Fat in vivo and mineralocorticoid receptor anti-thermogenic effects. Annales d’Endocrinologie vol. 80, n° 1, dir. {Elsevier Masson} p. 1-9
https://dx.doi.org/10.1016/j.ando.2018.04.018
Rataj Felicitas, Planel Séverine, Desroches-Castan Agnès, LeDouce Juliette, Lamribet Khadija, Denis Josiane, Feige Jean-Jacques & Cherradi Nadia, December 2016 — The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1. Molecular Biology of the Cell vol. 27, n° 24, dir. {American Society for Cell Biology} p. 3841-3854
https://dx.doi.org/10.1091/mbc.E16-06-0379
De Cian Anne, Guittat Lionel, Kaiser Markus, Saccà Barbara, Amrane Samir, Bourdoncle Anne, Alberti Patrizia, Teulade-Fichou Marie-Paule, Lacroix Laurent & Mergny Jean-Louis, June 2007 — Fluorescence-based melting assays for studying quadruplex ligands.. Methods vol. 42, n° 2, dir. {Elsevier} p. 183-95
https://dx.doi.org/10.1016/j.ymeth.2006.10.004
Sandoz Jérémy, Nagy Zita, Catez Philippe, Caliskan Gizem, Geny Sylvain, Renaud Jean-Baptiste, Concordet Jean-Paul, Poterszman Arnaud, Tora Làszlò, Egly Jean-Marc, Le May Nicolas & Coin Frédéric, December 2019 — Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression. Nature Communications vol. 10, n° 1, dir. {Nature Publishing Group} p. 1288
https://dx.doi.org/10.1038/s41467-019-09270-2
Charpentier M., Khedher A. H y, Menoret S., Brion A., Lamribet K., Dardillac E., Boix C., Perrouault L., Tesson L., Geny S., de Cian A., Itier J M, Anegon I., Lopez B., Giovannangeli C. et al., 2018 — CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair. Nature Communications vol. 9, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/s41467-018-03475-7
Torbey Patrick, Thierion Elodie, Collombet Samuel, de Cian Anne, Desmarquet-Trin-Dinh Carole, Dura Mathilde, Concordet Jean-Paul, Charnay Patrick & Gilardi-Hebenstreit Pascale, August 2018 — Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation. PLoS Genetics vol. 14, n° 8, dir. {Public Library of Science} e1007581
https://dx.doi.org/10.1371/journal.pgen.1007581
de Oliveira Vanessa Cristina, Gomes Mariano Junior Clésio, Belizário José Ernesto, Krieger José Eduardo, Fernandes Bressan Fabiana, Roballo Kelly Cristine Santos, Fantinato-Neto Paulo, Meirelles Flávio Vieira, Chiaratti Marcos Roberto, Concordet Jean-Paul & Ambrósio Carlos Eduardo, July 2020 — Characterization of post-edited cells modified in the TFAM gene by CRISPR/Cas9 technology in the bovine model. PLoS ONE vol. 15, n° 7, dir. {Public Library of Science} e0235856
https://dx.doi.org/10.1371/journal.pone.0235856
Mollà-Herman Anahi, Boularan Cédric, Ghossoub Rania, G.H.Scott Mark, Burtey Anne, Zarka Marion, Saunier Sophie, Concordet Jean-Paul, Marullo Stefano & Benmerah Alexandre R., November 2008 — Targeting of \beta-Arrestin2 to the Centrosome and Primary Cilium: Role in Cell Proliferation Control. PLoS ONE vol. 3, n° 11, dir. {Public Library of Science} e3728
https://dx.doi.org/10.1371/journal.pone.0003728
Amendola Mario, Bedel Aurélie, Buj-Bello Ana, Carrara Mathieu, Concordet Jean-Paul, Frati Giacomo, Gilot David, Giovannangeli Carine, Gutierrez-Guerrero Alejandra, Laurent Marine, Miccio Annarita, Moreau-Gaudry François, Sourd Célia, Valton Julien & Verhoeyen Els, October 2021 — Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Human Gene Therapy vol. 32, 19-20, dir. {Mary Ann Liebert} p. 1059-1075
https://dx.doi.org/10.1089/hum.2021.191
de Cian Anne, Praly Elise, Ding Fangyuan, Singh Vijender, Lavelle Christophe, Le Cam Eric, Croquette Vincent, Pietrement Olivier & Bensimon David, February 2012 — ATP-Independent Cooperative Binding of Yeast Isw1a to Bare and Nucleosomal DNA. PLoS ONE vol. 7, n° 2, dir. {Public Library of Science} e31845
https://dx.doi.org/10.1371/journal.pone.0031845
Joutsen Jenny, da Silva Alejandro Jose, Luoto Jens Christian, Budzynski Marek Andrzej, Nylund Anna Serafia, de Thonel Aurélie, Concordet Jean-Paul, Mezger Valérie, Sabéran-Djoneidi Délara, Henriksson Eva & Sistonen Lea, January 2020 — Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion. Cell Reports vol. 30, n° 2, dir. {Elsevier Inc} 583-597.e6
https://dx.doi.org/10.1016/j.celrep.2019.12.037
Bastin-Héline Lucie, de Fouchier Arthur A., Cao Song, Koutroumpa Fotini A., Caballero-Vidal Gabriela, Robakiewicz Stefania, Monsempes Christelle, Franç Marie-Christine, Ribeyre Tatiana, Maria Annick, Chertemps Thomas, de Cian Anne, Ill William B Walker, Wang Guirong, Jacquin-Joly Emmanuelle V et al., December 2019 — A novel lineage of candidate pheromone receptors for sex communication in moths. eLife vol. 8, , dir. {eLife Sciences Publication}
https://dx.doi.org/10.7554/eLife.49826
Pavani Giulia, Laurent Marine, Fabiano Anna, Cantelli Erika, Sakkal Aboud, Corre Guillaume, Lenting Peter J., Concordet Jean-Paul, Toueille Magali, Miccio Annarita & Amendola Mario, July 2020 — Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins. Nature Communications vol. 11, n° 1, dir. {Nature Publishing Group} p. 3778
https://dx.doi.org/10.1038/s41467-020-17552-3
Dreano Elise, Bacchetta Marc, Simonin Juliette, Galmiche Louise, Usal Claire, Slimani Lotfi, Sadoine Jérémy, Tesson Laurent, Anegon Ignacio, Concordet Jean-paul, Hatton Aurélie, Vignaud Lucile, Tondelier Danielle, Sermet-gaudelus Isabelle, Chanson Marc et al., November 2019 — Characterization of two rat models of cystic fibrosis-KO and F508del CFTR-Generated by Crispr-Cas9. Animal Model Exp Med / Animal models and experimental medicine. vol. 2, n° 4, dir. {[Hoboken, New Jersey] : John Wiley \& Sons, Inc., [2018]-} p. 297-311
https://dx.doi.org/10.1002/ame2.12091
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