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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • GE2R _ Genome Editing, DNA double-strand break Repair and cellular Responses
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Cacheux Lauriane, Ponger Loïc, Gerbault-Seureau Michèle, Richard Florence Anne & Escudé Christophe, 2016 — Diversity and distribution of alpha satellite DNA in the genome of an Old World monkey: Cercopithecus solatus. BMC Genomics vol. 17, , dir. {BioMed Central} p. 916
https://dx.doi.org/10.1186/s12864-016-3246-5
Blasimme Alessandro, Anegon Ignacio, Concordet Jean-Paul, deVos John, Dubart-Kupperschmitt Anne, Fellous Marc, Fouchet Pierre, Frydman Nelly, Giovannangeli Carine, Jouannet Pierre, Serre Jean-Loius, Steffann Julie, Rial-Sebbag Emmanuelle, Thomsen Mogens & Cambon-Thomsen Anne, December 2015 — Genome Editing and Dialogic Responsibility: “What’s in a Name?”. American Journal of Bioethics vol. 15, n° 12, dir. {Taylor \& Francis (Routledge)} p. 54-57
https://dx.doi.org/10.1080/15265161.2015.1103811
Ménoret Séverine, de Cian Anne, Tesson Laurent, Remy Séverine, Usal Claire, Boulé Jean-Baptiste, Boix Charlotte, Fontanière Sandra, Crénéguy Alison, Nguyen Tuan H., Brusselle Lucas, Thinard Reynald, Gauguier Dominique, Concordet Jean-Paul, Cherifi Yacine et al., October 2015 — Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins. Scientific Reports vol. 5, , dir. {Nature Publishing Group} p. 14410
https://dx.doi.org/10.1038/srep14410
Millet Armêl, Strauss Francois & Delagoutte Emmanuelle, October 2015 — Use of double-stranded DNA mini-circles to characterize the covalent topoisomerase-DNA complex. Scientific Reports vol. 5, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/srep13154
Jiang Kai, Zhang Ce, Guttula Durgarao, Liu Fan, van Kan Jeroen A, Lavelle Christophe, Kubiak Krzysztof, Malabirade Antoine, Lapp Alain, Arluison Véronique & van Der Maarel Johan R C, 2015 — Effects of Hfq on the conformation and compaction of DNA. Nucleic Acids Research vol. 43, n° 8, dir. {Oxford University Press} p. 4332-4341
https://dx.doi.org/10.1093/nar/gkv268
Audry Julien, Maestroni Laetitia, Delagoutte Emmanuelle, Gauthier Tiphaine, Nakamura Toru, Gachet Yannick, Saintomé Carole, Geli Vincent & Coulon Stephane, 2015 — RPA prevents G-rich structure formation at lagging- strand telomeres to allow maintenance of chromosome ends. EMBO Journal vol. 34, , dir. {EMBO Press} p. 1942-1958
https://dx.doi.org/10.15252/embj.201490773
Mendoza Oscar, Meriem Gueddouda Nassima, Boulé Jean-Baptiste, Bourdoncle Anne & Mergny Jean-Louis, 2015 — A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands. Nucleic Acids Research vol. 43, n° 11, dir. {Oxford University Press} e71
https://dx.doi.org/10.1093/nar/gkv193
Boulé Jean-Baptiste, Mozziconacci Julien & Lavelle Christophe, January 2015 — The Polymorphisms of the Chromatin Fiber. Journal of Physics: Condensed Matter vol. 27, n° 3, dir. {IOP Publishing}
https://dx.doi.org/10.1088/0953-8984/27/3/033101
Cayrol Bastien, Geinguenaud Frédéric, Lacoste Jérôme, Busi Florent, Le Derout Jacques, PIETREMENT Olivier, Le Cam Eric, Régnier Philippe, Lavelle Christophe & Arluison Véronique, October 2014 — Auto-assembly of E. coli DsrA small noncoding RNA: Molecular characteristics and functional consequences. RNA Biology vol. 6, n° 4, dir. {Taylor \\& Francis} p. 434-445
https://dx.doi.org/10.4161/rna.6.4.8949
Busi Florent, Cayrol Bastien, Lavelle Christophe, LeDerout Jacques, PIETREMENT Olivier, Le Cam Eric, Geinguenaud Frédéric, Lacoste Jérôme, Régnier Philippe & Arluison Véronique, October 2014 — Auto-assembly as a new regulatory mechanism of noncoding RNA. Cell Cycle vol. 8, n° 6, dir. {Taylor \\& Francis} p. 952-954
https://dx.doi.org/10.4161/cc.8.6.7905
Remy Séverine, Tesson Laurent, Ménoret Séverine, Usal Claire, De Cian Anne, Thepenier Virginie, Thinard Reynald, Baron Daniel, Charpentier Marine, Renaud Jean-Baptiste, Buelow Roland, Cost Gregory J., Giovannangeli Carine, Fraichard Alexandre, Concordet Jean-Paul et al., August 2014 — Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases. Genome Research vol. 24, n° 8, dir. {Cold Spring Harbor Laboratory Press} p. 1371-1383
https://dx.doi.org/10.1101/gr.171538.113
Ménoret Séverine, Tesson Laurent, Rémy Severine, Usal Claire, Thépenier Virginie, Thinard Reynald, Ouisse Laure-Hélène, De Cian Anne, Giovannangeli Carine, Concordet Jean-Paul & Anegon Ignacio, August 2014 — Gene targeting in rats using transcription activator-like effector nucleases. Methods vol. 69, n° 1, dir. {Elsevier} p. 102-107
https://dx.doi.org/10.1016/j.ymeth.2014.02.027
Safa Layal, Delagoutte Emmanuelle, Petruseva Irina, Alberti Patrizia, Lavrik Olga, Riou Jean-François & Saintomé Carole, August 2014 — Binding polarity of RPA to telomeric sequences and influence of G-quadruplex stability. Biochimie vol. 103, , p. 80-88
https://dx.doi.org/10.1016/j.biochi.2014.04.006
Pina Mery, Basta Tamara, Quax Tessa, Joubert Alexandra, Baconnais Sonia, Cortez Diego, Lambert Sarah, Le Cam Eric, Bell Stephen, Forterre Patrick & Prangishvili David, June 2014 — Unique genome replication mechanism of the archaeal virus AFV1. Molecular Microbiology vol. 92, n° 6, dir. {Wiley} p. 1313-1325
https://dx.doi.org/10.1111/mmi.12630
Huet Sébastien, Lavelle Christophe, Ranchon Hubert, Carrivain Pascal, Victor Jean-Marc & Bancaud Aurélien, 2014 — Relevance and limitations of crowding, fractal, and polymer models to describe nuclear architecture.. International Review of Cell and Molecular Biology vol. 307, , p. 443-79
https://dx.doi.org/10.1016/B978-0-12-800046-5.00013-8
Larcher Thibaut, Lafoux Aude, Tesson Laurent, Remy Severine, Thepenier Virginie, François Virginie, Le Guiner Caroline, Goubin Hélicia, Dutilleul Maeva, Guigand Lydie, Toumaniantz Gilles, de Cian Anne, Boix Charlotte, Renaud Jean-Baptiste, Cherel Yan et al., 2014 — Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy. PLoS ONE vol. 9, n° 10, dir. {Public Library of Science} 13 p.
https://dx.doi.org/10.1371/journal.pone.0110371
Rakkaa Tarik, Escudé Christophe, Giet Régis, Magnaghi-Jaulin Laura & Jaulin Christian, 2014 — CDK11p58 kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis. Chromosome Research vol. 22, n° 3, dir. {Springer Verlag} p. 267-276
https://dx.doi.org/10.1007/s10577-013-9400-x
Marlin Fanny, Simon Philippe, Bonneau Stéphanie, Alberti Patrizia, Cordier Céline, Boix Charlotte, Perrouault Loïc, Fossey Aurélie, Saison-Behmoaras Tula, Fontecave Marc & Giovannangeli Carine, November 2012 — Flavin Conjugates for Delivery of Peptide Nucleic Acids. ChemBioChem vol. 13, n° 17, dir. {Wiley-VCH Verlag}
https://dx.doi.org/10.1002/cbic.201200505
Bancaud Aurélien, Lavelle Christophe, Huet Sébastien & Ellenberg Jan, October 2012 — A fractal model for nuclear organization: current evidence and biological implications.. Nucleic Acids Research vol. 40, n° 18, dir. {Oxford University Press} p. 8783-92 Rapport LAAS n 11615
https://dx.doi.org/10.1093/nar/gks586
de Cian Anne, Praly Elise, Ding Fangyuan, Singh Vijender, Lavelle Christophe, Le Cam Eric, Croquette Vincent, Pietrement Olivier & Bensimon David, February 2012 — ATP-Independent Cooperative Binding of Yeast Isw1a to Bare and Nucleosomal DNA. PLoS ONE vol. 7, n° 2, dir. {Public Library of Science} e31845
https://dx.doi.org/10.1371/journal.pone.0031845
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