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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • GE2R _ Genome Editing, DNA double-strand break Repair and cellular Responses
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Safa Layal, Gueddouda Nassima Meriem, Thiébaut Frédéric, Delagoutte Emmanuelle, Petruseva Irina, Lavrik Olga, Mendoza Oscar, Bourdoncle Anne, Alberti Patrizia, Riou Jean-François & Saintomé Carole, 2016 — 5’ to 3’ Unfolding Directionality of DNA Secondary Structures by Replication Protein A. Journal of Biological Chemistry vol. 291, n° 40, dir. {American Society for Biochemistry and Molecular Biology} p. 21246-21256
https://dx.doi.org/10.1074/jbc.M115.709667
Audry Julien, Maestroni Laetitia, Delagoutte Emmanuelle, Gauthier Tiphaine, Nakamura Toru, Gachet Yannick, Saintomé Carole, Geli Vincent & Coulon Stephane, 2015 — RPA prevents G-rich structure formation at lagging- strand telomeres to allow maintenance of chromosome ends. EMBO Journal vol. 34, , dir. {EMBO Press} p. 1942-1958
https://dx.doi.org/10.15252/embj.201490773
Chatain Jean, Hatem Georges, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, September 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
https://dx.doi.org/10.1093/nar/gkab768
Lancrey Astrid, Safa Layal, Chatain Jean, Delagoutte Emmanuelle, Riou Jean-François, Alberti Patrizia & Saintomé Carole, March 2018 — The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units. Biochimie vol. 146, , dir. {Elsevier} p. 68-72
https://dx.doi.org/10.1016/j.biochi.2017.11.017
Saintomé Carole & Delagoutte Emmanuelle, August 2018 — Probing hyper-negatively supercoiled mini-circles with nucleases and DNA binding proteins. PLoS ONE vol. 13, n° 8, dir. {Public Library of Science} e0202138
https://dx.doi.org/10.1371/journal.pone.0202138
Safa Layal, Delagoutte Emmanuelle, Petruseva Irina, Alberti Patrizia, Lavrik Olga, Riou Jean-François & Saintomé Carole, August 2014 — Binding polarity of RPA to telomeric sequences and influence of G-quadruplex stability. Biochimie vol. 103, , p. 80-88
https://dx.doi.org/10.1016/j.biochi.2014.04.006
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Category

By authors

  • Patrizia ALBERTI
  • Carole SAINTOMÉ
  • (-) Emmanuelle DELAGOUTTE

Year

  • 2021
  • 2018
  • 2016
  • 2015
  • 2014

Affiliation entity

  • Équipe GPA
  • Équipe SANTÉ

Affiliation organism

  • CNRS
  • MNHN
  • (-) Sorbonne Université

Status

A research group
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    • Publications
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