Main collaborations
- Fabienne Aujard & Jeremy Terrien, MECADEV, MNHN CNRS, Brunoy
- Stéphane Coulon, Centre de Recherche en Cancérologie de Marseille Dennis Gomez & Sebastien Britton, Institut de Pharmacologie et de Biologie Structurale, CNRS, Toulouse
- Eric Defrancq & Olivier Lavergne, DCIM, Université de Grenoble-Alpes, CNRS, Grenoble
- Anton Granzhan & Marie-Paule Teulade-Fichou, Institut Curie, Orsay
- Caroline Kannengiesser, CHU Bichat, Paris
- Arturo Londono-Vallejo, Institut Curie, Paris
- Jean-Louis Mergny, Ecole Polytechnique, Palaiseau
- Marc Nadal & Terence Strick, Ecole Normale Supérieure, Paris
- Marie-Noelle Prioleau, Institut Jacques Monod, CNRS, Paris
- Patrick Revy, Institut Imagine, Paris
- Raphael Rodriguez, Institut Curie, Paris
Selected publications:
Bossaert M*, Pipier A*, Riou J-F, Noirot C, Nguyen L-T, Serre R-F, Bouchez O, Defrancq E, Calsou P, Britton S, Gomez D. Transcription-associated topoisomerase 2a (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands. eLife. 2021; 10: e65184.
Bugaut A, Alberti P. Understanding the stability of DNA G-quadruplex units in long human telomeric strands. Biochimie. 2015; 113:125-33.
Chatain J, Blond A, Phan AT, Saintomé C, Alberti P. GGGCTA repeats can fold into hairpins poorly unfolded by Replication Protein A: a possible origin of the length-dependent instability of GGGCTA variant repeats in human telomeres. Nucleic Acids Res. 2021; in press.
Hwang IP, Mailliet P, Hossard V, Riou JF, Bugaut A, Roger L. Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA). Molecules. 2019; 24(3):577.
Lancrey A, Safa L, Chatain J, Delagoutte E, Riou JF, Alberti P, Saintomé C. The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units. Biochimie. 2018; 146:68-72.
Le Berre G, Hossard V, Riou JF, Guieysse-Peugeot AL. Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. Int J Mol Sci. 2019;20(11):2791.
Lejault P. Ligands de la jonction double-brin/simple-brin de l’ADN télomérique comme sondes moléculaires pour étudier la biologie des télomères. PhD Thesis, ED 227 MNHN, 20 Nov 2017.
Pipier A, Devaux A, lavergne T, Adrait A, Couté Y, Britton S, Calsou P, Riou J-F, Defrancq E, Gomez D. Constrained G4 structures unveil topology specificity of known and new G4 binding proteins. Scientific Report. 2021; 11:13469
Subecz C, Sun JS, Roger L. Effect of DNA repair inhibitor AsiDNA on the incidence of telomere fusion in crisis. Hum Mol Genet. 2021; 30(3-4):172-181.
Trochet D, Mergui X, Ivkovic I, Porreca RM, Gerbault-Seureau M, Sidibe A, Richard F, Londono-Vallejo A, Perret M, Aujard F, Riou JF. Telomere regulation during ageing and tumorigenesis of the grey mouse lemur. Biochimie. 2015; 113:100-10.
