Carole SAINTOMÉ
Maître de Conférences
Chargé(e) d'enseignement
Entité de rattachement
Équipe SANTÉ
Contact
Courriel
carole.saintome[at]mnhn.fr
Téléphone
01 40 79 36 86
Adresse(s)
CNRS UMR 7196 / INSERM U1154
43, rue Cuvier - Case Postale 26
75231 Paris Cedex 05, France
Publications
2022
- , mars 2022 — Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue. Blood vol. 139, n° 7, p. 1039-1051
2021
- , septembre 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research vol. 49, , dir. {Oxford University Press} p. 10735-10746
- , juillet 2021 — GGGCTA repeats can fold into hairpins poorly unfolded by replication protein A: a possible origin of the length-dependent instability of GGGCTA variant repeats in human telomeres. Nucleic Acids Research , , dir. {Oxford University Press}
- , juin 2021 — The meiosis-specific MEIOB–SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex. DNA Repair vol. 102, , p. 103097
2020
- , août 2020 — Functional Diversification of Replication Protein A Paralogs and Telomere Length Maintenance in Arabidopsis. Genetics vol. 215, n° 4, p. 989-1002
- , 2020 — A multi-approach analysis highlights the relevance of RPA-1 as a telomere end-binding protein (TEBP) in Leishmania amazonensis. Biochimica et Biophysica Acta (BBA)-General Subjects vol. 1864, n° 7, p. 129607
2018
- , août 2018 — Probing hyper-negatively supercoiled mini-circles with nucleases and DNA binding proteins. PLoS ONE vol. 13, n° 8, dir. {Public Library of Science} e0202138
- , mars 2018 — The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units. Biochimie vol. 146, , dir. {Elsevier} p. 68-72
- , 2018 — Photoactivatable oligonucleotide probes to trap single-stranded DNA binding proteins: Updating the potential of 4-thiothymidine from a comparative study. Biochimie vol. 154, , dir. {Elsevier} p. 164-175
- , 2018 — Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures. Chemical Communications vol. 54, n° 15, dir. {Royal Society of Chemistry} p. 1897-1900