Les tutelles
MNHN - CNRS - Inserm
Jean-Paul CONCORDET et Carine GIOVANNANGELI,
Liste des publications
Novembre 2022 — Base-editing-mediated dissection of a \gamma-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression. Nature Communications. Vol. 13, n° 1, dir. Nature Publishing Group, p. 6618.
, Juin 2022 — Disease modeling by efficient genome editing using a near PAM-less base editor in vivo. Nature Communications. Vol. 13, n° 1, dir. Nature Publishing Group, p. 3435.
, Octobre 2021 — Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Human Gene Therapy. Vol. 32, 19-20, dir. Mary Ann Liebert, p. 1059-1075.
, Février 2020 — Editing a \gamma-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype. Science Advances. Vol. 6, n° 7, dir. American Association for the Advancement of Science (AAAS), eaay9392.
, 2019 — Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells. PLoS Genetics. Vol. 15, n° 10, dir. Public Library of Science, e1008355.
, 2018 — Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models. Transplantation. Vol. 102, n° 8, dir. Lippincott, Williams \& Wilkins, p. 1271-1278.
, Décembre 2018 — High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion. Scientific Reports. Vol. 8, n° 1, dir. Nature Publishing Group.
, Novembre 2017 — Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation. Scientific Reports. Vol. 7, n° 1, dir. Nature Publishing Group, p. 16554.
, Mars 2016 — Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases.. Cell Reports. Vol. 14, n° 9, dir. Elsevier Inc, p. 2263-72.
, 2016 — « Genome Editing in Rats Using TALE Nucleases » in TALENs. Methods in Molecular Biology. P. 245-259.
, Décembre 2015 — Genome Editing and Dialogic Responsibility: “What’s in a Name?”. American Journal of Bioethics. Vol. 15, n° 12, dir. Taylor \& Francis (Routledge), p. 54-57.
, Octobre 2015 — Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins. Scientific Reports. Vol. 5, dir. Nature Publishing Group, p. 14410.
, 2014 — Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy. PLoS ONE. Vol. 9, n° 10, dir. Public Library of Science, 13 p..
, Août 2014 — Gene targeting in rats using transcription activator-like effector nucleases. Methods. Vol. 69, n° 1, dir. Elsevier, p. 102-107.
, Août 2014 — Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases. Genome Research. Vol. 24, n° 8, dir. Cold Spring Harbor Laboratory Press, p. 1371-1383.
, Juillet 2008 — Triplex-forming oligonucleotide-orthophenanthroline conjugates for efficient targeted genome modification.. Proceedings of the National Academy of Sciences of the United States of
America. Vol. 105, n° 28, dir. National Academy of Sciences, p. 9576-81.
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