Les tutelles
MNHN - CNRS - Inserm
Jean-Paul CONCORDET,
Liste des publications
Novembre 2022 — Base-editing-mediated dissection of a \gamma-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression. Nature Communications. Vol. 13, n° 1, dir. Nature Publishing Group, p. 6618.
, 2022 — CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis. Human Molecular Genetics. Vol. 31, n° 1, dir. Oxford University Press (OUP), p. 41-56.
, Juin 2022 — Disease modeling by efficient genome editing using a near PAM-less base editor in vivo. Nature Communications. Vol. 13, n° 1, dir. Nature Publishing Group, p. 3435.
, Octobre 2021 — Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective. Human Gene Therapy. Vol. 32, 19-20, dir. Mary Ann Liebert, p. 1059-1075.
, Décembre 2021 — « Tagging Proteins with Fluorescent Reporters Using the CRISPR/Cas9 System and Double-Stranded DNA Donors » in Multiprotein Complexes. P. 39-57.
, 2021 — Gene Tagging with the CRISPR-Cas9 System to Facilitate Macromolecular Complex Purification. Methods in molecular biology (Clifton, N.J.). Vol. 2305, p. 153-174.
, Mars 2021 — Correction of \beta-thalassemia by CRISPR/Cas9 editing of the \alpha-globin locus in human hematopoietic stem cells. Blood Advances. Vol. 5, n° 5, dir. The American Society of Hematology, p. 1137-1153.
, Février 2021 — Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish. eLife. Vol. 10, dir. eLife Sciences Publication.
, Juillet 2020 — Characterization of post-edited cells modified in the TFAM gene by CRISPR/Cas9 technology in the bovine model. PLoS ONE. Vol. 15, n° 7, dir. Public Library of Science, e0235856.
, Janvier 2020 — Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion. Cell Reports. Vol. 30, n° 2, dir. Elsevier Inc, 583-597.e6.
, Février 2020 — Expression analysis data of BCL11A and \gamma-globin genes in KU812 and KG-1 cell lines after CRISPR/Cas9-mediated BCL11A enhancer deletion. Data in Brief. Vol. 28, dir. Elsevier, p. 104974.
, Juillet 2020 — Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins. Nature Communications. Vol. 11, n° 1, dir. Nature Publishing Group, p. 3778.
, Février 2020 — Editing a \gamma-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype. Science Advances. Vol. 6, n° 7, dir. American Association for the Advancement of Science (AAAS), eaay9392.
, Mars 2019 — Edition of TFAM gene by CRISPR/Cas9 technology in bovine model. PLoS ONE. Vol. 14, n° 3, dir. Public Library of Science, e0213376.
, Novembre 2019 — Characterization of two rat models of cystic fibrosis-KO and F508del CFTR-Generated by Crispr-Cas9. Animal Model Exp Med / Animal models and experimental medicine. Vol. 2, n° 4, dir. [Hoboken, New Jersey] : John Wiley \& Sons, Inc., [2018]-, p. 297-311.
, 2019 — Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells. PLoS Genetics. Vol. 15, n° 10, dir. Public Library of Science, e1008355.
, Juillet 2019 — Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease. European Journal of Pharmacology. Vol. 854, dir. Elsevier, p. 398-405.
, Août 2019 — Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation. PLoS Genetics. Vol. 15, n° 8, dir. Public Library of Science, e1008013.
, Décembre 2019 — Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression. Nature Communications. Vol. 10, n° 1, dir. Nature Publishing Group, p. 1288.
, 2018 — Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models. Transplantation. Vol. 102, n° 8, dir. Lippincott, Williams \& Wilkins, p. 1271-1278.
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