Les tutelles
MNHN - CNRS - Inserm
Jean-François RIOU,
Liste des publications
Juin 2021 — Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands. G-quadruplexes (G4) are non-canonical DNA structures found in the genome
of most species including human. Small molecules... eLife. Vol. 10, dir. eLife Sciences Publications, Ltd, e65184.
, ISSN:
2050-084X
Septembre 2021 — Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3’ toward 5’, a feature due to a 3’-end binding preference and to structuring of telomeric DNA. Nucleic Acids Research. Vol. 49, dir. Oxford University Press, p. 10735-10746.
, 2020 — AP-TSS: A New Method for the Analysis of RNA Expression from Particular and Challenging Transcription Start Sites. Biomolecules. Vol. 10, n° 6, dir. MDPI, p. 827.
, Juin 2020 — Sex-Specific Response to Caloric Restriction After Reproductive Investment in Microcebus murinus: An Integrative Approach. Frontiers in Physiology. Vol. 11, dir. Frontiers.
, Février 2019 — Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA). Molecules. Vol. 24, n° 3, dir. MDPI, p. 577.
, Juin 2019 — Repression of TERRA Expression by Subtelomeric DNA Methylation Is Dependent on NRF1 Binding. International Journal of Molecular Sciences. Vol. 20, n° 11, dir. MDPI, p. 2791.
, Mars 2018 — The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units. Biochimie. Vol. 146, dir. Elsevier, p. 68-72.
, 2018 — Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures. Chemical Communications. Vol. 54, n° 15, dir. Royal Society of Chemistry, p. 1897-1900.
, Février 2018 — Metabolic and genomic adaptations to winter fattening in a primate species, the grey mouse lemur (Microcebus murinus). International Journal of Obesity. Vol. 42, n° 2, dir. Nature Publishing Group, p. 221-230.
, 2016 — 5’ to 3’ Unfolding Directionality of DNA Secondary Structures by Replication Protein A. Journal of Biological Chemistry. Vol. 291, n° 40, dir. American Society for Biochemistry and Molecular Biology, p. 21246-21256.
, Juin 2015 — Telomere regulation during ageing and tumorigenesis of the grey mouse lemur. Biochimie. Vol. 113, dir. Elsevier, p. 100-110.
, Avril 2014 — G4 motifs affect origin positioning and efficiency in two vertebrate replicators.. EMBO Journal. Vol. 33, n° 7, dir. EMBO Press, p. 732-46.
, Septembre 2011 — An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies. Angewandte Chemie International Edition. Vol. 50, n° 37, dir. Wiley-VCH Verlag, p. 8745-8749.
, Juillet 2009 — 2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers. Bioorganic and Medicinal Chemistry Letters. Vol. 19, n° 13, dir. Elsevier, p. 3434-3438.
, Juillet 2006 — The G-quadruplex Ligand Telomestatin Inhibits POT1 Binding to Telomeric Sequences In vitro and Induces GFP-POT1 Dissociation from Telomeres in Human Cells. Cancer Research. Vol. 66, n° 14, dir. American Association for Cancer Research, p. 6908-6912.
, Décembre 2006 — Telomestatin-induced Telomere Uncapping Is Modulated by POT1 through G-overhang Extension in HT1080 Human Tumor Cells. Journal of Biological Chemistry. Vol. 281, n° 50, dir. American Society for Biochemistry and Molecular Biology, p. 38721-38729.
, Avril 2005 — Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence. Nucleic Acids Research. Vol. 33, n° 7, dir. Oxford University Press, p. 2192-2203.
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