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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Baudement Marie, Cournac Axel, Court Franck, Seveno Marie, Parrinello Hugues, Reynes Christelle, Sabatier Robert, Bouschet Tristan, Yi Zhou, Sallis Sephora, Tancelin Mathilde, Rebouissou Cosette, Cathala Guy, Lesne Annick, Mozziconacci Julien et al., November 2018 — High-salt Recovered Sequences are associated with the active chromosomal compartment and with large ribonucleoprotein complexes including nuclear bodies. Genome Research vol. 28, n° 11, dir. {Cold Spring Harbor Laboratory Press} p. 1733-1746
https://dx.doi.org/10.1101/gr.237073.118
Lema Ingrid J., Amazit Larbi, Lamribet Khadija, Fagart Jérome, Blanchard Anne, Lombès Marc, Cherradi Nadia & Viengchareun Say, December 2017 — HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis. Scientific Reports vol. 7, n° 1, dir. {Nature Publishing Group} p. 4835
https://dx.doi.org/10.1038/s41598-017-04838-8
Lema Ingrid J., Amazit Larbi, Lamribet Khadija, Fagart Jérome, Blanchard Anne, Lombès Marc, Cherradi Nadia & Viengchareun Say, December 2017 — RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity. Cellular and Molecular Life Sciences vol. 74, n° 24, dir. {Springer Verlag} p. 4587-4597
https://dx.doi.org/10.1007/s00018-017-2594-x
Viengchareun Say, Lema Ingrid J., Lamribet Khadija, Keo Vixra, Blanchard Anne, Cherradi Nadia & Lombès Marc, September 2014 — Hypertonicity Compromises Renal Mineralocorticoid Receptor Signaling through Tis11b-Mediated Post-Transcriptional Control. Journal of the American Society of Nephrology vol. 25, n° 10, dir. {American Society of Nephrology} p. 2213-2221
https://dx.doi.org/10.1681/ASN.2013091023
Kuhn Emmanuelle, Lamribet Khadija, Viengchareun Say, LeMenuet Damien, Fève Bruno & Lombès Marc, February 2019 — UCP1 transrepression in Brown Fat in vivo and mineralocorticoid receptor anti-thermogenic effects. Annales d’Endocrinologie vol. 80, n° 1, dir. {Elsevier Masson} p. 1-9
https://dx.doi.org/10.1016/j.ando.2018.04.018
Rataj Felicitas, Planel Séverine, Desroches-Castan Agnès, LeDouce Juliette, Lamribet Khadija, Denis Josiane, Feige Jean-Jacques & Cherradi Nadia, December 2016 — The cAMP pathway regulates mRNA decay through phosphorylation of the RNA-binding protein TIS11b/BRF1. Molecular Biology of the Cell vol. 27, n° 24, dir. {American Society for Cell Biology} p. 3841-3854
https://dx.doi.org/10.1091/mbc.E16-06-0379
Roger Lauréline, Jullien Laurent, Gire Véronique & Roux Pierre, April 2010 — Gain of oncogenic function of p53 mutants regulates E-cadherin expression uncoupled from cell invasion in colon cancer cells.. Journal of Cell Science vol. 123, Pt 8, dir. {Company of Biologists} p. 1295-305
https://dx.doi.org/10.1242/jcs.061002
De Toledo Marion, Anguille Christelle, Roger Lauréline, Roux Pierre & Gadéa Gilles, November 2012 — Cooperative Anti-Invasive Effect of Cdc42/Rac1 Activation and ROCK Inhibition in SW620 Colorectal Cancer Cells with Elevated Blebbing Activity. PLoS ONE vol. 7, n° 11, dir. {Public Library of Science} e48344
https://dx.doi.org/10.1371/journal.pone.0048344
Dorleans Audrey, Gigant Benoît, Ravelli Raimond, Mailliet Patrick, Mikol Vincent & Knossow Marcel, August 2009 — Variations in the colchicine-binding domain provide insight into the structural switch of tubulin. Proceedings of the National Academy of Sciences of the United States of America vol. 106, n° 33, dir. {National Academy of Sciences} p. 13775-13779
https://dx.doi.org/10.1073/pnas.0904223106
Douarre Céline, Gomez Dennis, Morjani Hamid, Zahm Jean-Marie, O’Donohue Marie-Françoise, Eddabra Lahcen, Mailliet Patrick, Riou Jean-Francois & Trentesaux Chantal, April 2005 — Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence. Nucleic Acids Research vol. 33, n° 7, dir. {Oxford University Press} p. 2192-2203
https://dx.doi.org/10.1093/nar/gki514
Alberti Alberto, Robino Patrizia, Chessa Bernardo, Rosati Sergio, Addis Maria Filippa, Mercier Pascale, Mannelli Alessandro, Cubeddu Tiziana, Profiti Margherita, Bandino Ennio, Thiery Richard & Pittau Marco, February 2008 — Characterisation of P60 surface lipoprotein and its evaluation in a recombinant ELISA. Veterinary Microbiology vol. 128, 1-2, dir. {Elsevier} p. 81
https://dx.doi.org/10.1016/j.vetmic.2007.09.020
De Cian Anne, Guittat Lionel, Kaiser Markus, Saccà Barbara, Amrane Samir, Bourdoncle Anne, Alberti Patrizia, Teulade-Fichou Marie-Paule, Lacroix Laurent & Mergny Jean-Louis, June 2007 — Fluorescence-based melting assays for studying quadruplex ligands.. Methods vol. 42, n° 2, dir. {Elsevier} p. 183-95
https://dx.doi.org/10.1016/j.ymeth.2006.10.004
Ferraro Daniela, Tredici Ilenia G., Ghigna Paolo, Castillio-Michel Hiram, Falqui Andrea, Di Benedetto Cristiano, Alberti Giancarla, Ricci Vittorio, Anselmi-Tamburini Umberto & Sommi Patrizia, 2017 — Dependence of the Ce(III)/Ce(IV) ratio on intracellular localization in ceria nanoparticles internalized by human cells. Nanoscale vol. 9, n° 4, dir. {Royal Society of Chemistry} p. 1527-1538
https://dx.doi.org/10.1039/c6nr07701c
Bugaut Anthony & Alberti Patrizia, June 2015 — Understanding the stability of DNA G-quadruplex units in long human telomeric strands. Biochimie vol. 113, , dir. {Elsevier} p. 125-133
https://dx.doi.org/10.1016/j.biochi.2015.04.003
Gurung Pratima, Gomes Ana Rita, Martins Rafael, Juranek Stefan, Alberti Patrizia, Mbang-Benet Diane-Ethna, Urbach S, Gazanion Elodie, Guitard Vincent, Paeschke Katrin & Lopez-Rubio José Juan, April 2021 — PfGBP2 is a novel G-quadruplex binding protein in Plasmodium falciparum. Cellular Microbiology vol. 23, n° 4, dir. {Wiley} e13303
https://dx.doi.org/10.1111/cmi.13303
Saintomé C., Alberti Patrizia, Guinot N., Lejault P., Chatain J., Mailliet P., Riou Jean-Francois & Bugaut A., 2018 — Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures. Chemical Communications vol. 54, n° 15, dir. {Royal Society of Chemistry} p. 1897-1900
https://dx.doi.org/10.1039/c7cc07048a
Gazanion Elodie, Lacroix Laurent, Alberti Patrizia, Gurung Pratima, Wein Sharon, Cheng Mingpan, Mergny Jean-louis, Gomes Ana Rita & Lopez‑rubio José‑juan, July 2020 — Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites. PLoS Genetics vol. 16, n° 7, dir. {Public Library of Science} e1008917
https://dx.doi.org/10.1371/journal.pgen.1008917
Sandoz Jérémy, Nagy Zita, Catez Philippe, Caliskan Gizem, Geny Sylvain, Renaud Jean-Baptiste, Concordet Jean-Paul, Poterszman Arnaud, Tora Làszlò, Egly Jean-Marc, Le May Nicolas & Coin Frédéric, December 2019 — Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression. Nature Communications vol. 10, n° 1, dir. {Nature Publishing Group} p. 1288
https://dx.doi.org/10.1038/s41467-019-09270-2
Amrane Samir, Kerkour Abdelaziz, Bedrat Amina, Vialet Brune, Andreola Marie-Line & Mergny Jean-Louis, April 2014 — Topology of a DNA G-quadruplex structure formed in the HIV-1 promoter: a potential target for anti-HIV drug development.. Journal of the American Chemical Society vol. 136, , dir. {American Chemical Society} p. 5249-52
https://dx.doi.org/10.1021/ja501500c
Charpentier M., Khedher A. H y, Menoret S., Brion A., Lamribet K., Dardillac E., Boix C., Perrouault L., Tesson L., Geny S., de Cian A., Itier J M, Anegon I., Lopez B., Giovannangeli C. et al., 2018 — CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair. Nature Communications vol. 9, n° 1, dir. {Nature Publishing Group}
https://dx.doi.org/10.1038/s41467-018-03475-7
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