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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Astrid Lancrey, Alexandra Joubert, Evelyne Duvernois-Berthet, Etienne Routhier, Saurabh Raj, Agnès Thierry, Marta Sigarteu, Loic Ponger, Vincent Croquette, Julien Mozziconacci, Jean-Baptiste Boulé, 2022 — Nucleosome positioning on large tandem DNA repeats of the ’601’ sequence engineered in Saccharomyces cerevisiae. Journal of Molecular Biology vol. 434, n° 1, p. 15
https://dx.doi.org/167497
Krämer Andreas, Tjaden Amelie, Ndreshkjana Benardina, Tredup Claudia, Farin Henner, Knapp Stefan, Janin Yves & Müller Susanne, 2022 — IPP/CNRS-A017: A chemical probe for human dihydroorotate dehydrogenase (hDHODH). Current Research in Chemical Biology vol. 2, , p. 100034
https://dx.doi.org/10.1016/j.crchbi.2022.100034
Legrand Pierre & Janin Yves, November 2022 — On Reuben G. Jones synthesis of 2-hydroxypyrazines. Beilstein Journal of Organic Chemistry vol. 18, , dir. {Beilstein-Institut} p. 935-943 Poster
https://dx.doi.org/10.3762/bjoc.18.93
Steed Emily, Faggianelli Nathalie, Roth Stephane, Ramspacher Caroline, Concordet Jean-Paul & Vermot Julien, 2016 — klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. Nature Communications vol. 7, , dir. {Nature Publishing Group} p. 11646
https://dx.doi.org/10.1038/ncomms11646
Valle-Orero Jessica, Rieu Martin, Tran Phong Lan Thao, Joubert Alexandra, Raj Saurabh, Allemand Jean-François, Croquette Vincent & Boulé Jean-Baptiste, August 2022 — Strand switching mechanism of Pif1 helicase induced by its collision with a G-quadruplex embedded in dsDNA. Nucleic Acids Research , , dir. {Oxford University Press}
https://dx.doi.org/10.1093/nar/gkac667
Pavani Giulia, Fabiano Anna, Laurent Marine, Amor Fatima, Cantelli Erika, Chalumeau Anne, Maule Giulia, Tachtsidi Alexandra, Concordet Jean-Paul, Cereseto Anna, Mavilio Fulvio, Ferrari Giuliana, Miccio Annarita & Amendola Mario, March 2021 — Correction of \beta-thalassemia by CRISPR/Cas9 editing of the \alpha-globin locus in human hematopoietic stem cells. Blood Advances vol. 5, n° 5, dir. {The American Society of Hematology} p. 1137-1153
https://dx.doi.org/10.1182/bloodadvances.2020001996
Boisard Julie, Duvernois-Berthet Evelyne, Duval Linda, Schrével Joseph, Guillou Laure, Labat Amandine, Le Panse Sophie, Prensier Gérard, Ponger Loïc & Florent Isabelle, December 2022 — Marine gregarine genomes reveal the breadth of apicomplexan diversity with a partially conserved glideosome machinery. BMC Genomics vol. 23, n° 1, dir. {BioMed Central} p. 485
https://dx.doi.org/10.1186/s12864-022-08700-8
Babin Loélia, Darchen Alice, Robert Elie, Aid Zakia, Borry Rosalie, Soudais Claire, Piganeau Marion, de Cian Anne, Giovannangeli Carine, Bawa Olivia, Rigaud Charlotte, Scoazec Jean-Yves, Couronné Lucile, Veleanu Layla, Cieslak Agata et al., December 2022 — De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells. Molecular Cancer vol. 21, n° 1, dir. {BioMed Central} p. 65
https://dx.doi.org/10.1186/s12943-022-01520-0
Sun Jian-Sheng, October 2022 — « Histoire(s) de la vie » in La Terre, le vivant, les humains : Petites et grandes découvertes de l’Histoire naturelle.. , , p. 128-143
https://hal-mnhn.archives-ouvertes.fr/mnhn-03879810
Kay Tomas, Helleu Quentin & Keller Laurent, August 2022 — Iterative evolution of supergene-based social polymorphism in ants. Philosophical Transactions of the Royal Society B vol. 377, n° 1856, dir. {Royal Society, The} p. 20210196
https://dx.doi.org/10.1098/rstb.2021.0196
Rosello Marion, Serafini Malo, Mignani Luca, Finazzi Dario, Giovannangeli Carine, Mione Marina C, Concordet Jean-Paul & del Bene Filippo, June 2022 — Disease modeling by efficient genome editing using a near PAM-less base editor in vivo. Nature Communications vol. 13, n° 1, dir. {Nature Publishing Group} p. 3435
https://dx.doi.org/10.1038/s41467-022-31172-z
Philippe Florian, Dubrulle Nelly, Marteaux Benjamin, Bonnet Brice, Choisy Patrick, Berthon Jean-yves, Garnier Laurence, Leconte Nadine, Milesi Sandrine, Morvan Pierre-yves, Saunois Alex, Sun Jian-sheng, Weber Sandrine & Giraud Nicole, February 2022 — Combining DNA Barcoding and Chemical fingerprints to authenticate Lavender raw material. International Journal of Cosmetic Science vol. 44, n° 1, dir. {Wiley} p. 91-102
https://dx.doi.org/10.1111/ics.12757
Mérien Antoine, Tahraoui-Bories Julie, Cailleret Michel, Dupont Jean-Baptiste, Leteur Céline, Polentes Jérôme, Carteron Alexandre, Polvèche Hélène, Concordet Jean-Paul, Pinset Christian, Jarrige Margot, Furling Denis & Martinat Cécile, 2022 — CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis. Human Molecular Genetics vol. 31, n° 1, dir. {Oxford University Press (OUP)} p. 41-56
https://dx.doi.org/10.1093/hmg/ddab218
Janin Yves, 2022 — On drug discovery against infectious diseases and academic medicinal chemistry contributions. Beilstein Journal of Organic Chemistry vol. 18, , dir. {Beilstein-Institut} p. 1355-1378
https://dx.doi.org/10.3762/bjoc.18.141
Sun Jian-Sheng, October 2021 — « L’interdépendance des vivants et le concept One Health (une seule santé) : l’exemple de l’émergence du virus Nipah » in Quel futur pour le vivant ?.. , , dir. {Editions de l'aube} p. 103-111
https://hal-mnhn.archives-ouvertes.fr/mnhn-03890896
Eveno Mégane, Savard Patricia, Belguesmia Yanath, Bazinet Laurent, Gancel Frédérique, Drider Djamel & Fliss Ismail, February 2021 — Compatibility, Cytotoxicity, and Gastrointestinal Tenacity of Bacteriocin-Producing Bacteria Selected for a Consortium Probiotic Formulation to Be Used in Livestock Feed. Probiotics and Antimicrobial Proteins vol. 13, n° 1, p. 208-217
https://dx.doi.org/10.1007/s12602-020-09687-y
Geny Sylvain, Pichard Simon, Poterszman Arnaud & Concordet Jean-Paul, 2021 — Gene Tagging with the CRISPR-Cas9 System to Facilitate Macromolecular Complex Purification. Methods in molecular biology (Clifton, N.J.) vol. 2305, , p. 153-174
https://dx.doi.org/10.1007/978-1-0716-1406-8_8
Yan Zheng, Martin Simon H, Gotzek Dietrich, Arsenault Samuel V, Duchen Pablo, Helleu Quentin, Riba-Grognuz Oksana, Hunt Brendan G, Salamin Nicolas, Shoemaker DeWayne & others, February 2020 — Evolution of a supergene that regulates a trans-species social polymorphism. Nature Ecology & Evolution vol. 4, n° 2, dir. {Nature} p. 240-249
https://dx.doi.org/10.1038/s41559-019-1081-1
Helleu Quentin & Levine Mia T, 2018 — Recurrent Amplification of the Heterochromatin Protein 1 (HP1) Gene Family across Diptera. Molecular Biology and Evolution vol. 35, n° 10, dir. {Oxford University Press (OUP)} p. 2375-2389
https://dx.doi.org/10.1093/molbev/msy128
Herath Nirmitha, Devun Flavien, Herbette Aurélie, Lienafa Marie-Christine, Chouteau Philippe, Sun Jian-Sheng, Dutreix Marie & Denys Alban, October 2017 — Potentiation of doxorubicin efficacy in hepatocellular carcinoma by the DNA repair inhibitor DT01 in preclinical models. European Radiology vol. 27, n° 10, dir. {Springer Verlag} p. 4435-4444
https://dx.doi.org/10.1007/s00330-017-4792-1
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