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Le laboratoire Structure et Instabilité des génomes UMR 7196 / U1154 est une unité mixte de recherche sous la co-tutelle du Muséum national d'Histoire naturelle, du Centre national de la Recherche Scientifique (CNRS), et de l’Institut national de la santé et de la recherche médicale (Inserm).
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    • GE2R _ Genome Editing, DNA double-strand break Repair and cellular Responses
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UMR 7196 - U1154 - Structure et Instabilité des Génomes
UMR 7196 - U1154

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Baltzer Agnès, Reynaud Marine, Ehrhold Axel, Fournier Jérôme, Cordier Céline, and Clouet Hélène. 2017. “Space-Time Evolution of a Large Field of Pockmarks in the Bay of Concarneau (NW Brittany)”. Bulletin de la Société Géologique de France 188 (January). {Soci{\’e}t{\’e} g{\’e}ologique de France}: 23. doi:10.1051/bsgf/2017191.
https://dx.doi.org/10.1051/bsgf/2017191
Martel-Frachet Véronique, Keramidas Michelle, Nurisso Alessandra, Debonis Salvatore, Rome Claire, Coll Jean-Luc, Boumendjel Ahcène, Skoufias Dimitrios, and Ronot Xavier. 2015. “IPP51, a Chalcone Acting As a Microtubule Inhibitor With in Vivo Antitumor Activity Against Bladder Carcinoma”. Oncotarget 6 (June). {Impact journals}: 14669-86. https://hal.archives-ouvertes.fr/hal-01234550.
https://hal.archives-ouvertes.fr/hal-01234550
Lancrey Astrid, Joubert Alexandra, and Boulé Jean-Baptiste. 2018. “Locus Specific Engineering of Tandem DNA Repeats in the Genome of Saccharomyces Cerevisiae Using CRISPR Cas9 and Overlapping Oligonucleotides”. Scientific Reports 8 (May). {Nature Publishing Group}. doi:10.1038/s41598-018-25508-3.
https://dx.doi.org/10.1038/s41598-018-25508-3
Qiao Qin, Le Manach Séverine, Huet Hélène, Duvernois-Berthet Evelyne, Chaouch Soraya, Duval Charlotte, Sotton Benoit, et al. 2016. “An Integrated Omic Analysis of Hepatic Alteration in Medaka Fish Chronically Exposed to Cyanotoxins With Possible Mechanisms of Reproductive Toxicity”. Environmental Pollution 219 (January). {Elsevier}: 119-31. doi:10.1016/j.envpol.2016.10.029.
https://dx.doi.org/10.1016/j.envpol.2016.10.029
Haeussler Maximilian, Schönig Kai, Eckert Hélène, Eschstruth Alexis, Mianné Joffrey, Renaud Jean-Baptiste, Schneider-Maunoury Sylvie, et al. 2016. “Evaluation of Off-Target and On-Target Scoring Algorithms and Integration into the Guide RNA Selection Tool CRISPOR”. Genome Biology 17 (July). {BioMed Central}: 148. doi:10.1186/s13059-016-1012-2.
https://dx.doi.org/10.1186/s13059-016-1012-2
Crut Aurelien, Géron-Landre Bénédicte, Bonnet Isabelle, Bonneau Stéphane, Desbiolles Pierre, and Escudé Christophe. 2005. “Detection of Single DNA Molecules by Multicolor Quantum-Dot End-Labeling”. Nucleic Acids Research 33 (June). {Oxford University Press}: e98-e98. doi:10.1093/nar/gni097.
https://dx.doi.org/10.1093/nar/gni097
Safa Layal, Gueddouda Nassima Meriem, Thiébaut Frédéric, Delagoutte Emmanuelle, Petruseva Irina, Lavrik Olga, Mendoza Oscar, et al. 2016. “5’ to 3’ Unfolding Directionality of DNA Secondary Structures by Replication Protein A”. Journal of Biological Chemistry 291 (January). {American Society for Biochemistry and Molecular Biology}: 21246-56. doi:10.1074/jbc.M115.709667.
https://dx.doi.org/10.1074/jbc.M115.709667
Qiao Qin, Le Manach Séverine, Sotton Benoit, Huet Hélène, Duvernois-Berthet Evelyne, Paris Alain, Duval Charlotte, et al. 2016. “Deep Sexual Dimorphism in Adult Medaka Fish Liver Highlighted by Multi-Omic Approach”. Scientific Reports 6 (January). {Nature Publishing Group}: 32459. doi:10.1038/srep32459.
https://dx.doi.org/10.1038/srep32459
Marlin Fanny, Simon Philippe, Bonneau Stéphanie, Alberti Patrizia, Cordier Céline, Boix Charlotte, Perrouault Loïc, et al. 2012. “Flavin Conjugates for Delivery of Peptide Nucleic Acids”. ChemBioChem 13 (November). {Wiley-VCH Verlag}. doi:10.1002/cbic.201200505.
https://dx.doi.org/10.1002/cbic.201200505
Ménoret Séverine, de Cian Anne, Tesson Laurent, Remy Séverine, Usal Claire, Boulé Jean-Baptiste, Boix Charlotte, et al. 2015. “Homology-Directed Repair in Rodent Zygotes Using Cas9 and TALEN Engineered Proteins”. Scientific Reports 5 (October). {Nature Publishing Group}: 14410. doi:10.1038/srep14410.
https://dx.doi.org/10.1038/srep14410
Tran Phong Lan Thao, Mergny Jean-Louis, and Alberti Patrizia. 2011. “Stability of Telomeric G-Quadruplexes”. Nucleic Acids Research 39 (April). {Oxford University Press}: 3282-94. doi:10.1093/nar/gkq1292.
https://dx.doi.org/10.1093/nar/gkq1292
Dheur Sonia, and Saison-Behmoaras Tula. 2000. “Polyethyleneimine-Mediated Transfection to Improve Antisense Activity of 3’-Capped Phosphodiester Oligonucleotides”. In Methods in Enzymology, 313:56-73. doi:10.1016/S0076-6879(00)13005-8.
https://dx.doi.org/10.1016/S0076-6879(00)13005-8
Rakkaa Tarik, Escudé Christophe, Giet Régis, Magnaghi-Jaulin Laura, and Jaulin Christian. 2014. “CDK11p58 Kinase Activity Is Required to Protect Sister Chromatid Cohesion at Centromeres in Mitosis”. Chromosome Research 22 (January). {Springer Verlag}: 267-76. doi:10.1007/s10577-013-9400-x.
https://dx.doi.org/10.1007/s10577-013-9400-x
Boudvillain Marc, Guerin Martine, Dalbies Rozenn, Saison-Behmoaras Tula, and Leng Marc. 1997. “Transplatin-Modified Oligo(2‘- O -Methyl Ribonucleotide)s: A New Tool for Selective Modulation of Gene Expression †”. Biochemistry 36 (March). {American Chemical Society}: 2925-31. doi:10.1021/bi962695f.
https://dx.doi.org/10.1021/bi962695f
Auer Thomas O., Xiao Tong, Bercier Valerie, Gebhardt Christoph, Duroure Karine, Concordet Jean-Paul, Wyart Claire, et al. 2015. “Deletion of a Kinesin I Motor Unmasks a Mechanism of Homeostatic Branching Control by Neurotrophin-3”. ELife 4 (June). {eLife Sciences Publication}: e05061. doi:10.7554/eLife.05061.030.
https://dx.doi.org/10.7554/eLife.05061.030
Hamon Florian, Largy Eric, Guødin-Beaurepaire Aurore, Rouchon-Dagois Myriam, Sidibe Assitan, Monchaud David, Mergny Jean-Louis, et al. 2011. “An Acyclic Oligoheteroaryle That Discriminates Strongly Between Diverse G-Quadruplex Topologies”. Angewandte Chemie International Edition 50 (September). {Wiley-VCH Verlag}: 8745-49. doi:10.1002/anie.201103422.
https://dx.doi.org/10.1002/anie.201103422
Renaud Jean-Baptiste, Boix Charlotte, Charpentier Marine, deCian Anne, Cochennec Julien, Duvernois-Berthet Evelyne, Perrouault Loïc, et al. 2016. “Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides With TALEN and CRISPR-Cas9 Nucleases”. Cell Reports 14 (March). {Elsevier Inc}: 2263-72. doi:10.1016/j.celrep.2016.02.018.
https://dx.doi.org/10.1016/j.celrep.2016.02.018
Solé Anna, Delagoutte Emmanuelle, Ciudad Carlos, Noé Véronique, and Alberti Patrizia. 2017. “Polypurine Reverse-Hoogsteen (PPRH) Oligonucleotides Can Form Triplexes With Their Target Sequences Even under Conditions Where They Fold into G-Quadruplexes”. Scientific Reports 7 (February). {Nature Publishing Group}. doi:10.1038/srep39898.
https://dx.doi.org/10.1038/srep39898
Cordier Céline, Boutimah Fatima, Bourdeloux Mathilde, Dupuy Florian, Met Elisabeth, Alberti Patrizia, Loll François, Chassaing Gérard, Burlina Fabienne, and Saison-Behmoaras Tula Ester. 2014. “Delivery of Antisense Peptide Nucleic Acids to Cells by Conjugation With Small Arginine-Rich Cell-Penetrating Peptide (R W)9”. PLoS ONE 9 (August). {Public Library of Science}: e104999. doi:10.1371/journal.pone.0104999.
https://dx.doi.org/10.1371/journal.pone.0104999
Coquery Nicolas, Pannetier Nicolas, Farion Régine, Herbette Aurélie, Azurmendi Leire, Clarencon Didier, Bauge Stéphane, et al. 2012. “Distribution and Radiosensitizing Effect of Cholesterol-Coupled Dbait Molecule in Rat Model of Glioblastoma”. PLoS ONE 7 (January). {Public Library of Science}: e40567. doi:10.1371/journal.pone.0040567.
https://dx.doi.org/10.1371/journal.pone.0040567
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